版块导航: 正在加载中...

登录注册

应《网络安全法》要求，自2017年10月1日起，未进行实名认证将不得使用互联网跟帖服务。为保障您的帐号能够正常使用，请尽快对帐号进行手机号验证，感谢您的理解与支持！

24小时热门版块排行榜

北京石油化工学院2026年研究生招生接收调剂公告

返回列表

当前主题已经存档。

hejin04c

荣誉版主 (著名写手)

小木虫乐乐虫

ECEPI: 12
应助: 2 (幼儿园)
贵宾: 0.551
金币: 5312.1
散金: 266
红花: 9
沙发: 1
帖子: 1441
在线: 193.6小时
虫号: 694727
注册: 2009-01-22
性别: MM
专业: 电化学分析
管辖: 电化学

[交流] 【专题】每日文献一篇

Letter

--------------------------------------------------------------------------------

Nature Nanotechnology
Published online: 17 January 2010 | doi:10.1038/nnano.2009.457

Article Links

Rohan Fernandes
Varnika Roy
Hsuan-Chen Wu
William E. Bentley
Engineered biological nanofactories trigger quorum sensing response in targeted bacteria
Rohan Fernandes1,2, Varnika Roy2,3, Hsuan-Chen Wu1,2 & William E. Bentley1,2

--------------------------------------------------------------------------------

AbstractBiological nanofactories, which are engineered to contain modules that can target, sense and synthesize molecules, can trigger communication between different bacterial populations. These communications influence biofilm formation1, 2, virulence3, 4, bioluminescence5, 6 and many other bacterial functions7, 8 in a process called quorum sensing9. Here, we show the assembly of a nanofactory that can trigger a bacterial quorum sensing response in the absence of native quorum molecules. The nanofactory comprises an antibody (for targeting) and a fusion protein that produces quorum molecules when bound to the targeted bacterium. Our nanofactory selectively targets the appropriate bacteria and triggers a quorum sensing response when added to two populations of bacteria. The nanofactories also trigger communication between two bacterial populations that are otherwise non-communicating. We envision the use of these nanofactories in generating new antimicrobial treatments that target the communication networks of bacteria rather than their viability.

--------------------------------------------------------------------------------
j积极交流，就可以拿金币哦，切忌不要灌水！

[ Last edited by hejin04c on 2010-1-22 at 11:01 ]

回复此楼

» 猜你喜欢

欲得其中，必求其上；欲得其上，必求上上

1楼 2010-01-22 10:45:20

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖