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★ ★ ★ ★ ★ ★ guoxiali(金币+6,VIP+0):谢谢了,嘻嘻... 1-20 18:09
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这是个更高级的质谱技术,主要是这种技术无需准备样品,而实际测量时所用的普通样品。在电离子化吸收方面,它能直接作用于测量物体。具体信息如下:A recent innovation in mass spectrometry is the ability to record mass spectra on ordinary samples, in their native environment, without sample preparation or preseparation by creating ions outside the instrument. In desorption electrospray ionization (DESI), the principal method described here, electrically charged droplets are directed at the ambient object of interest; they release ions from the surface, which are then vacuumed through the air into a conventional mass spectrometer. Extremely rapid analysis is coupled with high sensitivity and high chemical specificity. These characteristics are advantageously applied to high-throughput metabolomics, explosives detection, natural products discovery, and biological tissue imaging, among other applications. Future possible uses of DESI for in vivo clinical analysis and its adaptation to portable mass spectrometers are described. |
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