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luizing

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[½»Á÷] Çó·­ÒëÒ»¶Î½Ï¶ÌµÄÓ¢ÎÄ----ÔÚÏߵȰ¡ ÔÙ×·¼Ó10½ð±Ò

Several reasons could explain these discrepancies:for instance,it is
possible that the overexpression strategies used by ref.5 could have
distinct consequences compared with those that are extrapolated from
our deletion studies.Additionally,in our work,miR-223 is absent in
the entire granulocytic lineage in a mouse,whereas ref.5 manipulated
expression of miR-223 in a leukaemic cell line resembling an early
granulocyte progenitor.This issue is more relevant given that our data
provide evidence for distinct functions of miR-223 during different
stages of myeloid cell development,during which microRNA concen-
trations change dynamically.Future experiments aimed at manipulat-
ing miR-223 expression at defined granulocyte differentiation stages
will be useful in determining the multiple roles of this microRNA.

[ Last edited by luizing on 2010-1-10 at 21:03 ]

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goodtimega

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luizing(½ð±Ò+10,VIP+0): 1-11 20:44
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