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zap65535木虫 (著名写手)
两院大学士后
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[交流]
【生化环境类英译汉】+【紧急之三，至今日下午3点】
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| Abstract. Sixteen animals affected in 2 outbreaks of pet food–associated renal failure (2 dogs in 2004; 10 cats and 4 dogs in 2007) were evaluated for histopathologic, toxicologic, and clinicopathologic changes. All 16 animals had clinical and laboratory evidence of uremia, including anorexia, vomiting, lethargy, polyuria, azotemia, and hyperphosphatemia. Where measured, serum hepatic enzyme concentrations were normal in animals from both outbreaks. All animals died or were euthanized because of severe uremia. Distal tubular lesions were present in all 16 animals, and unique polarizable crystals with striations were present in distal tubules or collecting ducts in all animals. The proximal tubules were largely unaffected. Crystals and histologic appearance were identical in both outbreaks. A chronic pattern of histologic change, characterized by interstitial fibrosis and inflammation, was observed in some affected animals. Melamine and cyanuric acid were present in renal tissue from both outbreaks. These results indicate that the pet food–associated renal failure outbreaks in 2004 and 2007 share identical clinical, histologic, and toxicologic findings, providing compelling evidence that they share the same causation. |
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Abstract. Sixteen animals affected in 2 outbreaks of pet food–associated renal failure (2 dogs in 2004; 10 cats and 4 dogs in 2007) were evaluated for histopathologic, toxicologic, and clinicopathologic changes. All 16 animals had clinical and laboratory evidence of uremia, including anorexia, vomiting, lethargy, polyuria, azotemia, and hyperphosphatemia. Where measured, serum hepatic enzyme concentrations were normal in animals from both outbreaks. All animals died or were euthanized because of severe uremia. 摘要：对16只在2次宠物食物有关的肾衰竭爆发期患病动物（2004年2条狗，2007年10只猫和4条狗）的组织病理学，毒理学，临床病理学变化进行了评估。患病动物在临床上和实验室都表现出血尿，还有缺氧，呕吐，行动迟缓，多尿症，氮质血症以及高磷酸盐血症等。两次爆发期间，所有动物血清肝药酶浓度经检测均为正常。因为血尿病情严重，所有动物或病死或实施安乐死。 |
2楼2009-12-11 13:51:54
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zap65535(金币+33,VIP+0): 12-11 14:40
zap65535(金币+33,VIP+0): 12-11 14:40
| 摘要：对16只在2次宠物食物有关的肾衰竭爆发期患病动物（2004年2条狗，2007年10只猫和4条狗）的组织病理学，毒理学，临床病理学变化进行了评估。患病动物在临床上和实验室都表现出血尿，还有缺氧，呕吐，行动迟缓，多尿症，氮质血症以及高磷酸盐血症等。两次爆发期间，所有动物血清肝药酶浓度经检测均为正常。因为血尿病情严重，所有动物或病死或实施安乐死。16只患病动物的远端输尿管均表现损伤，而且其远端输尿管或集尿管均有独一的，有条纹的，可极化的晶体析出。近端的输尿管基本没有病变，在析晶和组织学方面，两次病情表现相同。一些患病动物上表现出以间质性纤维化和炎症为特征的慢性组织学变化。两次爆发期，在（患病动物）肾组织中均形成三聚氰胺和氰尿酸。这些结果表明，发生在2004年和2007年的这2次宠物食物有关的肾衰竭在临床上，组织学上和毒理学上表现相同，为证明两次病情由相同病因引起提供了有力的证据。 |
3楼2009-12-11 14:28:21
