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A new production release of UCSF Chimera (version 1.4) is now available from:
http://www.cgl.ucsf.edu/chimera/download.html

Download is free for noncommercial use.  Chimera is available for Windows, Mac Aqua, Mac/X11, and Linux. The download includes full documentation and tutorials.

Many improvements and new features have been added since the previous production release (Dec 2008), as listed in the release notes:
http://www.cgl.ucsf.edu/chimera/docs/relnotes/1.4.html

For the time-challenged, here are just a few of the reasons you may want to use the new version:

1) appearance:
- friendlier initial display, similar to ribbons preset
- CA-only and P-only structures can be shown as smooth tubes
- rings can be filled, aromatic rings shown with circles
- improved transparent surfaces (single-layer, etc.)
- glossy lighting option on many platforms
- anisotropic B-factors can be shown as ellipsoids
- surface coloring by Coulombic electrostatic potential
- 2D labels new font options, can be hidden/shown
- labels can be moved with the mouse
- improved single-sequence display
- offscreen rendering on most platforms

2) I/O:
- Blast protein tool uses Web service hosted by our lab;
   * hits can be shown as sequence alignment
   * corresponding structures (if any) can be retrieved
- new fetch type EMDB with keyword search
- can set download directory for caching fetched files
- Gromacs 4 trajectories supported

3) analysis and editing:
- planes can be defined from sets of atoms, used in
   distance and angle measurements (with atoms and axes)
- many more options for volume data filtering, processing  
- new measure command performs several calculations
   on structures, surfaces, and maps
- structure-based sequence alignment tool (Match->Align)
   can iterate to consistency

4) scripting:
- improved  movement commands (rock, roll, turn, move,
   reset), visual effect commands (surftransparency, set),
   new commands (coordset, fly, pause) for movie scripting
- volume planes playback (volume command)
- bond rotation (rotation command)
- nucleotide displays (nucleotides)
- symmetry copy generation (sym)
- runscript command for running python scripts
   with command-line arguments

See the release notes and User's Guide for more details.
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