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Please upload the following items:

1. A thorough, point-by-point response to each point raised, specifically describing all changes, or the reason why no change was made. This document should be uploaded as "Response to Reviews".

2. A copy of the revised manuscript that has all changes made in response to these comments clearly indicated (preferably underlined in red). Please identify this marked copy on the title page and in the file name. This document should be uploaded as a "Marked Manuscript".

3. A complete unmarked copy (i.e. Word, WordPerfect, RTF, or LaTex) of the revised manuscript.

4. Figures should be uploaded individually as TIF or EPS files with the figure number clearly indicated in the file name.

Thank you for your cooperation.

We look forward to receiving your revised manuscript.

Kind regards,

Journal Manager
Journal of Chromatography B

Comments:

Editor: I beleive this manuscript would be more appropriate as a short communication. I would be willing to reconsider this manuscript for external review if the authors change the manuscript into such a format.


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