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This effect seems to be mediated by activation of the cAMP pathway, which leads to the activation of the transcription factor cAMP-responsive-element (CRE)-binding protein (CREB) and to the direct induction of the Bdnf gene via a CRE site in its promoter ÕâÖÖÐ§Ó¦ËÆºõÊÇͨ¹ý cAMP ;¾¶½éµ¼µÄ£¬Ëüµ¼ÖÂÁËת¼Òò×ÓCREBµÄ¼¤»î£¬Í¨¹ýCREλµã£¬×÷ΪÆô¶¯×Ó£¬Ö±½ÓÓÕµ¼BNNF»ùÒò£¿ direct induction of the Bdnf gene via a CRE site in its promoter ÓÈÆäÊÇÕâ¾ä£¬ÔõôÀí½â£¿ |
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cjunxing
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hillpeng(½ð±Ò+6,VIP+0): 11-19 23:01
hillpeng(½ð±Ò+6,VIP+0): 11-19 23:01
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¸ÃÐ§Ó¦ËÆºõÊÇΪcAMP;¾¶µÄ¼¤»îËù½éµ¼µÄ, ¶øºóÕß¼¤»îÁËת¼Òò×Ó----cAMPÏìÓ¦Ôª¼þ½áºÏµ°°×, ²¢ÇÒ¾ÓÉÆäÆô¶¯×ÓÉϵÄcAMPÏìÓ¦Ôª¼þλµãÖ±½ÓÓÕµ¼Bdnf»ùÒò. [ Last edited by cjunxing on 2009-11-19 at 21:34 ] |
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