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广东医科大学黄遵楠教授课题组接收一专硕和一学硕药学研究生
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Sample Text 导师及平台简介 黄遵楠教授，海归博士、三级教授、博士生导师和博士后合作导师 。现任广东医科大学研究生院副院长、东莞市计算机辅助药物设计重点实验室主任、附属东莞第一医院药学部学术主任，以及广东省大数据挖掘和精准药物设计创新团队负责人 。黄教授2013年入选广东省“扬帆计划”引进紧缺拔尖人才，2023年获评东莞市特色人才，2025年获评中国商业联合会全国服务业科技创新人物 。 课题组目前已主持包括国家自然科学基金面上项目2项及省部级等科研课题9项，总经费达1000余万元 。黄教授在国内外学术期刊上发表学术论文160余篇，其中SCI论文130篇（含高被引论文3篇），累计影响因子680余分，Google Scholar他引4300余次，H指数32 。同时担任六个SCI期刊客座执行主编或学术编辑，以及六十多个SCI期刊审稿人 。 主要研究方向： 课题组致力于大数据挖掘和精准药物设计的科研工作，研究领域横跨计算生物学、生物信息学、分子生物学、病理生理学、药理学、中药学以及临床医学 。目前具体研究方向包括： · 中药新药研究和新制剂的研发，以及中药复方抗病分子机制网络药理学研究 · 人工智能和药物设计新算法和新程序 。 · 小分子抗肿瘤药物设计及其分子作用机制研究 。 · 肿瘤关键基因的功能和分子机制研究 。 · 基于大数据挖掘的分子预后或诊断标志物研发 。 · 循证医学、孟德尔随机化和（网状）荟萃分析 课题组优势与学生培养（干货满满！） 课题组科研氛围浓厚，对学生的科研训练极其扎实，学生培养硕果累累！加入我们，你将拥有最高效的产出平台： · 指导本科学生以第一作者（含共同）发表SCI论文35篇 。 · 指导学生荣获省“挑战杯”一等奖6项、二等奖3项、三等奖2项 。 · 指导学生获得第十届全国生命科学竞赛三等奖，以及第十三届“嬴在广州”暨粤港澳大湾区大学生创业大赛项目创新奖 。 调剂/招生要求： 1：具有药学、化学、生物学、生物信息学、计算机科学或临床医学等相关专业背景皆可。 2：勤奋踏实、有责任心、热爱科学研究并具有良好的团队协作精神。 3：具有良好的英语听说读写能力，能够独立或在指导下撰写英文报告和论文。 校园环境： 广东医科大学东莞校区所在的松山湖科技园区绿化面积超过60%，环境优美，空气质量高，气候四季如春非常宜人，是潜心学术的绝佳之地，欢迎大家加入我们！ 联系方式： 有意向调剂或报考的同学，请将个人简历（含考研各科成绩、生化/计算机等相关技能、四六级成绩等）发送至邮箱： liqourleon@gmail.com (来信邮件标题请严格遵循格式：姓名 - 本科学校 - 初试总分 - 报考专业 - 调剂意向) 24年以来以通讯和共同通讯发表的文章： 103. Haitham Ahmed Al-Madhagi#, Muhammad shahab#, Zheng Guojun, Gamil Al-Madhagy, Mohammed Bourhia, Gamal A. Shazly, Musaab Dauelbait*, Zunnan Huang*, “Engineering of the melanoma inhibitor of apoptosis (ML-IAP) anti-cancer peptide through a comprehensive in silico approaches”, Human Mutation, in press, (2026) (SCI IF:3.7) 102. Lishan Wang#, Jiaojiao Wang#, Dongli Yang, Kai Zhuang, Jiazhuo Xiao, Zhuolun Tang, Muhammad Waqas, Lin Yan, Zunnan Huang*, “Unraveling the Oncogenic and Immunosuppressive Roles of the FACT Complex in Pan-Cancer Through Multi-Omics and Single-Cell Analysis”, Big Data Mining and Analytics, in press, (2026) (SCI IF: 6.2) 101. Kai Zhuang#, Lin Yan#, Muhammad Waqas, Haixin Feng, Siqi Tang, Haoqi He, Xinshi Yu, Yanling Wang*, Zunnan Huang*, “Unveiling the Impact of Copper Metabolism on Epithelial-Mesenchymal Transition of Triple-Negative Breast Cancer: Identification of Therapeutic Targets”, Interdisciplinary Sciences - Computational Life Sciences, in press, (2026) (SCI IF: 3.9) 100. Muhammad Waqas, Li Xuan, Amjad Ali, Haoke Zhang, Zunnan Huang*, “Structural and Dynamic Characterization of SARS-CoV-2 Papain-Like Protease Bound to Machine-Learning-Identified Oxadiazole Inhibitors”, Journal of Molecular Structure, 1361: 145582 (2026) (SCI IF: 4.7) 99. Muhammad Waqas#, Syed Ahsan Shahid#, Muhammad Shahab, Yongkun Zhu, Aamir Fahira, Zunnan Huang*, “Structural and Computational Analysis of Monkeypox Virus Methyltransferase: Dynamic Inhibition Mechanisms and Their Implications for Antiviral Design”, Molecular Diversity, 30(1):1623-1644 (2026) (最新 SCI IF: 3.8) 98. Aamir Fahira#, Kai Zhuang#, Xuemin Jian, Syed Mansoor Jan, Liu Yong, Jianbo Sun, Yongyong Shi*, Zunnan Huang*, “Genetic Crosstalk Between Type 1 Diabetes and Sjögren's Syndrome: A Systematic Exploration of Risk Genes and Common Pathways”, Journal of Cellular and Molecular Medicine, 29(22): e70930 (2025) (最新SCI IF: 4.2) 98. Qianling Guo#, Dongli Yang#, Aamir Fahira, Qiusheng Zhong, Jiahao Yang, Kai Zhuang, Ying Wen, Zhuolun Tang, Zunnan Huang*, “Dissecting Causal Relationships Between Gut Microbiota Imbalance, Inflammatory Cytokines, and Structural Connectivity in the Brain: A Mendelian Randomization Study”, Brain and Behavior, 11(15): e70980 (2025) (最新 SCI IF: 2.7) 97. Muhammad Shahab, Muhammad Waqas, Aamir Fahira, Haoke Zhang, Zunnan Huang*, “Structure-Guided Discovery of Ubiquitin-Specific Protease 7 Inhibitors through Integrative Quantitative Structure-Activity Relationship Modeling, Docking, and Molecular Dynamics”, Computers in Biology and Medicine, 198, 111246 (2025) (最新 SCI IF: 6.3) 96. Yuqing Zhang, Wei Wu, Yuling Li, Jiaen Huang , Jiaxi Chen*, Rui Chen, Qiudi Mei, Zunnan Huang*, Jing Sun*, “Cyclometallated Ir(III) complexes exhibit antitumor activity, through angiogenesis inhibition”, Bioorganic Chemistry, 164, 108908, (2025) (最新 SCI IF: 4.7) 95. Ying Liu#, Jiayi Cai#, Aamir Fahira#, Kai Zhuang, Jiaojiao Wang, Zhi Zhang, Lin Yan, Yong Liu, Defang Ouyang*, Zunnan Huang*, “Unveiling the impact of interferon genes on the immune microenvironment of triple-negative breast cancer: identification of therapeutic targets”, Frontiers in Bioinformatics, 5: 1629526 (2025) (最新 SCI IF：3.9) 94. Muhammad Shahab#, Jiazhuo Xiao#, Haoke Zhang, Zunnan Huang*, “Support Vector Machine Classification-Guided Identification of Novel Monoamine Oxidase-B Inhibitors via Structure-Based Modeling to Treat Neurodegenerative Diseases”, International Journal of Biological Macromolecules, 322:146932 (2025) (最新 SCI IF: 8.5) 92. Muhammad Shahab, Muhammad Waqas, Aamir Fahira, Bharat Prasad Sharma, Haoke Zhang, Guojun Zheng*, Zunnan Huang*, “Machine Learning-Based Screening and Molecular Simulations for Discovering Novel PARP-1 Inhibitors Targeting DNA Repair Mechanisms for Breast Cancer Therapy”, Molecular Diversity, 29(4): 3323-3343 (2025) (最新 SCI IF: 3.8) 91. Liyi Zou#, Taomin Zhang#, Cui Yang#, Weijing Liu, Aamir Fahira, Dongli Yang, Biao Zheng, Xiaojun Yao*, Yi Liu*, Zunnan Huang*, “Downregulation of SLC7A11 by Bis(4-hydroxy-3,5-dimethylphenyl) sulfone induces ferroptosis in hepatocellular carcinoma cell”, Molecular Carcinogenesis, 64(3), 580–596 (2025) (最新 SCI IF: 3.2) 90. Weile Ye#, Pinglian Yang#, Mei Jin#, Jiami Zou, Zhihua Zheng, Yuanyuan Li, Dongmei Zhang, Wencai Ye, Zunnan Huang*, Jiaojiao Wang*, Zhiping Liu*, “Dihydromyricetin mitigates abdominal aortic aneurysm via transcription and post-transcriptional regulation of heme oxygenase-1 in vascular smooth muscle cells”, Acta Pharmaceutica Sinica B, 15(3), 1514-1534 (2025) (最新 SCI IF: 14.6) 89. Zhi Chen#, Yishan Guo#, Yuwei Peng#, Xiaojun Tan, Haoxiong Chen, Daqiang Luo, Kaixuan Luo, Dudu Wu, Zunnan Huang*, Zhiqiang Yu*, Cheng Tao*, “Synthesis and biological evaluation of novel isatin-phenol hybrids as potential antitumor agents”, Bioorganic Chemistry, 157: 108232 (2025) (最新 SCI IF: 4.7) 88. Yulai Tang#, Aamir Fahira#, Siying Lin, Yiming Shao, Zunnan Huang*, “Shared and specific competing endogenous RNAs network mining in four digestive system tumors”, Computational and Structural Biotechnology Journal, 23, 4271-4287 (2024) (SCI IF: 4.1) 87. Jiaojiao Wang#, Weile Ye#, Jiami Zou#, Pinglian Yang, Mei Jin, Zhihua Zheng, Chunhong Zhou, Wanlu Qiu, Jing Lu, Chengzhi Li, Shuai Guo, Yiming Xu, Zunnan Huang*, Peiqing Liu*, Zhiping Liu*, “Targeting the smooth muscle cell Keap1-Nrf2-GSDMD-pyroptosis axis by cryptotanshinone prevents abdominal aortic aneurysm formation”, Theranostics, 14(17), 6516-6542 (2024) (SCI IF: 13.3) 86. Muhammad Shahab, Muhammad Waqas, Aamir Fahira, Haoke Zhang, Guojun Zheng*, Zunnan Huang*, “Investigating the role of PmrB mutation on Colistin antibiotics drug resistance in Klebsiella Pneumoniae”, International Journal of Biological Macromolecules, 281(3): 136414 (2024) (SCI IF: 8.5) 85. Yong Liao#, Pinglian Yang#, Cui Yang, Kai Zhuang, Aamir Fahira, Jiaojiao Wang, Zhiping Liu, Lin Yan, Zunnan Huang*, “Clinical Signature and Associated Immune Metabolism of NLRP1 in Pan-Cancer”, Journal of Cellular and Molecular Medicine, 28(18): e70100 (2024) (SCI IF: 4.2) 84. Pengfei Xu*, Zunnan Huang*, Yanyong Xu*, Huanxiang Liu*, Yuyu Liu*, Ling Wang*, “Editorial: Antioxidants and inflammatory immune-related diseases”, Frontiers in Immunology, 5: 1476887 (2024) (SCI IF: 5.9) 83. Aamir Fahira, Ali Alamdar Shah Syed, Xuemin Jian, Qiangzhen Yang, Chenxiang Zheng, Abdul Wadood, Zhuo Wang, Zunnan Huang*, Yongyong Shi*, “Genome-wide association of Common Genetic Variants and Functional Annotation Analysis of Schizophrenia and White Matter Abnormalities”, Asian Journal of Psychiatry, 102: 104236 (2024) (SCI IF: 4.5) 82. Jiaqi Yu#, Jiayi Cai#, Aamir Fahira, Keyong Liao, Yani Tongjia, Yiming Shao, Zunnan Huang∗, “A Comprehensive Investigation to Identify Prognostic mRNA and miRNA Signatures for Renal Cell Carcinoma Utilizing a Stratification-based Approach”, Big Data Mining and Analytics, 7(4), 1396-1416 (2024) (SCI IF: 6.2) 81. Kai Zhuang#, Lishan Wang#, Chengyu Lu#, Zhiping Liu#, Dongli Yang, Hao Zhong, Jiami Zou, Aamir Fahira, Jiaojiao Wang*, Zunnan Huang*, “Assessment of SWI/SNF Chromatin Remodeling Complex Related Genes as Potential Biomarkers and Therapeutic Targets in Pan-cancer”, Molecular Cancer, 23(1): 176 (2024) (SCI IF: 33.9) 80. Lanmei Chen, Hong Tang, Tianling Hu, Jie Wang, Qianqian Ouyang, Xufeng Zhu*, Rui Wang, Wenyong Huang, Zunnan Huang*, Jincan Chen*, “Three Ru (II) complexes modulate the antioxidant transcription factor Nrf2 to overcome cisplatin resistance”, Journal of Inorganic Biochemistry, 259: 112666 (2024) (SCI IF: 3.2) 79. Yuqing Zhang#, Yao Gong#, Zhijun Liang#, Wei Wu, Jiaxi Chen∗, Yuling Li, Rui Chen, Jun Mei, Zunnan Huang*, Jing Sun*, “Mitochondria- and endoplasmic reticulum-localizing iridium (III) complexes induce immunogenic cell death of 143B cells”, Journal of Inorganic Biochemistry, 259: 112655 (2024) (SCI IF: 3.2) 78. Jiaojiao Wang#, Yong Liao#, Pinglian Yang, Weile Ye, Yong Liu, Chunxia Xiao, Weixiong Liao, Chunbo Chen*, Zhiping Liu*, Zunnan Huang*, “Multi-Omics reveals influenza-A virus target genes associated genomic, clinical and immunological features in cancers”, Biomedical and Environmental Sciences, 37(7), 698-715 (2024) (SCI IF: 4.1) 77. Yong Liu#, Junzhang Zhao#, Baoxiang Huang#, Youcheng Liang, Guanming Jiang, Xinglin Zhou, Yilin Chen, Tao He, Mingbin Zheng*, Zunnan Huang*, “Identification and validation of an immunotherapeutic signature for colon cancer based on the regulatory patterns of ferroptosis and their association with the tumor microenvironment”, Biochmica et Biophysica Acta - Molecular Cell Research, 1871(4):119698 (2024) (SCI IF: 3.7) 76. Ling Qin, Boya Li, Shijie Wang, Yulai Tang, Aamir Fahira, Yanqi Kou, Tong Li, Zhigang Hu*, Zunnan Huang*, “Construction of an Immune-Related Prognostic Signature and lncRNA‒miRNA–mRNA ceRNA Network in Acute Myeloid Leukaemia”, Journal of Leukocyte Biology, 116(1), 146-165 (2024) (SCI IF: 3.1) 75. Lanmei Chen, Wenzhu Yu, Hong Tang, Shenting Zhang, Jie Wang, Qianqian Ouyang, Miao Guo, Xufeng Zhu*, Zunnan Huang*, Jincan Chen*, “Cyclometalated ruthenium complexes overcome cisplatin resistance through PI3K/mTOR/Nrf2 signaling pathway”, Metallomics, 16(1): mfae002 (2024) (SCI IF: 2.9) 74. Liyi Zou#, Xiaodan Li#, Jiansuo Lin, Xuehong Fang, Jie Lin, Lu Zhang, Yan Zhang, Yanwen Liang, Jianwei Ren, Yi Liu*, Zunnan Huang*, “Ethyl 2,2-difluoro-2-(2-oxo-2H-chromen-3-yl) acetate attenuates the malignant biological behaviors of non-small cell lung cancer via suppressing EGFR/PI3K/AKT/mTOR signaling pathway”, Journal of Pharmacy and Pharmacology, 76(3), 269-282 (2024) (SCI IF: 3.2) 73. Yongjian Su#, Xiaoqing Zhang#, Youcheng Liang, Jianbo Sun, Chengyu Lu*, Zunnan Huang*, “Integrated analysis of single-cell RNA-seq and bulk RNA-seq to unravel the molecular mechanisms underlying the immune microenvironment in the development of intestinal-type gastric cancer”, Biochimica et Biophysica Acta - Molecular Basis of Disease, 1870(1): 166849 (2024) (SCI IF: 6.2) 72. Nanlian Pan#, Yuqing Zhang#, Minying Huang#, Zhijun Liang, Yao Gong, Xide Chen*, Yuling Li, Ciling Wu, Zunnan Huang*, Jing Sun*, “Lysosome-targeted ruthenium (II) complex encapsulated with pluronic@ F-127 induces oncosis in A549 cells”, Journal of Biological Inorganic Chemistry, 29(2), 265-278 (2024) (SCI IF: 2.7) 71. Kai Zhuang#, Siqi Tang#, Haixin Feng#, Jinying Zhang, Ying Liu, Yong Liu, Yongjian Su, Jiaqi Yu, Zunnan Huang*, “A novel copper metabolism-related signature model predicting the prognosis, target drugs, and immunotherapy in stomach adenocarcinoma”, Genes & Diseases, 11(5): 101102 (2024) (最新 SCI IF: 9.4) |
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