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ÊìÁ·ÕÆÎÕ»ùÒò¿Ë¡¡¢µ°°×ÖÊÓëRNA±í´ï´¿»¯µÈÉúÎﻯѧÓë·Ö×ÓÉúÎïѧʵÑé¼¼Êõ£» 3. ¶Ô¿ÆÑ§Ñо¿¾ßÓÐÇ¿ÁÒÐËȤ£¬Ì¤Êµ¿Ï¸É£¬¾ßÓнÏÇ¿µÄ¶¯ÊÖÄÜÁ¦£¬ÍŶÓÐ×÷¾«Éñ¼°ÔðÈÎÐÄ¡£ Èý¡¢¸Úλ´ýÓö£º °´ÕÕÖпÆÔºÉúÎïÎïÀíËùµÄÏà¹Ø¹æ¶¨£¬ÏíÊÜÖпÆÔºÉúÎïÀíËùºÏͬƸÓÃÖÆ£¨·ÇÊÂÒµµ¥Î»±àÖÆ£©´ýÓö£¬²¢¸ù¾Ý¸öÈ˱³¾°Ìṩ¶îÍâ²¹Öú£¬¾ßÌå´ýÓöÃæÒé¡£±íÏÖÓÅÐãÕß¿ÉÍÆ¼ö½øÒ»²½ÉîÔ죨±¾¿ÆÉúÍÆ¼ö˶ʿÑо¿ÉúÏÄÁîÓª»ú»á£¬Ë¶Ê¿ÉúÍÆ¼öÆÕ²©Éú»ú»á£©¡£ ËÄ¡¢ÕÐÆ¸·½Ê½£º ӦƸÕßÇëÓÚ2025Äê12ÔÂ20ÈÕǰ½«±¾ÈËÏêϸ¼òÀú¼°¿ÉÒÔ¿ªÊ¼¹¤×÷µÄʱ¼äͨ¹ýµç×ÓÓʼþ·¢ÖÁ: fxy_ncrna@163.com, ²¢ÔÚÓʼþ±êÌâ×¢Ã÷¡°Ó¦Æ¸¿ÆÑÐÖúÀí-±¾ÈËÐÕÃû¡±¡£ÎÒÃǽ«Í³Ò»°²ÅÅÃæÊÔʱ¼ä¡£ Îå¡¢¿ÎÌâ×é½üÆÚ·¢±íÂÛÎÄ£º 1. Xiaolin Niu#, Shanshan Cai#, Junzheng Wang, Chunlai Chen*, Xianyang Fang*. tRNA-dependent conformational dynamics and folding coordinate translational regulation by a full-length T-box riboswitch. Nature Communications 2025, Accepted in press. 2. Meishuo Liu#, Keyun Huang#, Jie Zhang#, Qingyang Li, Xinming Wang, Buming Gu, Hao Tang, Zhenhai Du, LiangJun Hu, Shutao Qi, Yu Ma, Hongtao Yu, Wei Xie*, Xianyang Fang*, Haifeng Wang*. CRISPR live-cell imaging reveals chromatin dynamics and enhancer interactions at multiple non-repetitive loci. Nature Biotechnology 2025, doi: 10.1038/s41587-025-02887-3. 3. Jie Zhang, Xianyang Fang*. Empowering the molecular ruler techniques with unnatural base pair system to explore conformational dynamics of flaviviral RNAs. Current Opinion in Structural Biology 2024, 89: 102944. 4. Yufan Zhang# , Zhonghe Xu# , Yu Xiao# , Haodong Jiang# , Xiaobing Zuo , Xing Li*, Xianyang Fang*. Structural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST. Nature Communications 2024, 15(1):4206 5. Xiaolin Niu, Zhonghe Xu, Yufan Zhang, Xiaobing Zuo, Chunlai Chen*, Xianyang Fang*. Structural and dynamic mechanisms for coupled folding and tRNA recognition of a translational T-box riboswitch. Nature Communications 2023, 14(1):7394. 6. Xiang Chen#, Yan Wang#, Zhonghe Xu#, Meng-Li Cheng, Qing-Qing Ma, Rui-Ting Li, Zheng-Jian Wang, Hui Zhao, Xiaobing Zuo, Xiao-Feng Li, Xianyang Fang*, Cheng-Feng Qin*. Zika virus RNA structure controls its unique neurotropism by bipartite binding to Musashi-1. Nature Communications 2023, 14(1): 1134 7. Lilei Xu#, Yu Xiao#, Jie Zhang, Xianyang Fang*. Structural insights into translation regulation by THF-II riboswitch. Nucleic Acids Research 2023, 51(2):952-965. 8. Xianyang Fang*, Jose Gallego*, Yun-Xing Wang*. Deriving RNA topological structure from SAXS. Methods in Enzymology 2022, 677:479-529. 9. Yanping Hu#, Yan Wang#, Jaideep Singh#£¬Ruirui Sun#, Lilei Xu, Xiaolin Niu, Keyun Huang, Guangcan Bai, Guoquan Liu, Xiaobing Zuo, Chunlai Chen, Peter Z. Qin, Xianyang Fang*. Phosphorothioate-based posttranscriptional site-specific labeling of large RNAs for structural and dynamic studies. ACS Chemical Biology 2022, 17(9):2448-2460 10. Burkhard Endeward#, Yanping Hu#, Guangcan Bai, Guoquan Liu, Thomas F. Prisner*, Xianyang Fang*. Long-range distance determination in fully deuterated RNA with pulsed EPR spectroscopy. Biophysical Journal 2022£¬121(1):37-43. 11. Xiaolin Niu#, Ruirui Sun#, Zhifeng Chen, Yirong Yao, Xiaobing Zuo, Chunlai Chen*, Xianyang Fang*. Pseudoknot length modulates the folding, conformational dynamics and robustness of Xrn1 resistance of flaviviral xrRNAs. Nature Communications 2021, 12(1): 6417 12. Junfeng Ma, Xiang Cheng, Zhonghe Xu, Yikan Zhang, Jaione Valle, Shilong Fan, Xiaobing Zuo, Inigo Lasa, Xianyang Fang*. Structural mechanism for modulation of functional amyloid and biofilm formation by Staphylococcal Bap protein switch. The EMBO Journal 2021, 40(14): e107500. (Research Highlight on Nature Chemical Biology 2021, 17: 839) 13. Xiaolin Niu#, Qiuhan Liu#, Zhonghe Xu#, Zhifeng Chen, Linghui Xu, Lilei Xu, Jinghong Li*, Xianyang Fang*. Molecular mechanisms underlying the mechanical anisotropy of flaviviral exoribonuclease-resistant RNAs (xrRNAs). Nature Communications 2020, 11(1): 5496. (News and Views on Nature Chemical Biology 2021, 17: 933-934) 14. Yan Wang, Venkatesan Kathiresan, Yaoyi Chen, Yanping Hu, Wei Jiang, Guangcan Bai, Guoquan Liu, Peter Z. Qin*, Xianyang Fang*. Posttranscriptional site-directed spin labeling of large RNAs with an unnatural base pair system under non-denaturing conditions. Chemical Science 2020, 11: 9655-9664. 15. Yan Wang, Yaoyi Chen, Yanping Hu, Xianyang Fang*. Site-specific covalent labeling of large RNAs with nanoparticles empowered by expanded genetic alphabet transcription. Proceedings of the National Academy of Sciences 2020, 117(37): 22823-22832. 16. Yupeng Zhang#, Yikan Zhang#, Zhong-Yu Liu#£¬Meng-Li Cheng#, Junfeng Ma, Yan Wang, Cheng-Feng Qin*, Xianyang Fang*. Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Reports 2019, 20(11): e47016. [ À´×Ô°æ¿éȺ ±±¾© ] |
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