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Ñо¿·½Ïò£º Éñ¾ËðÉËÓëÐÞ¸´ 3. Ô´´ÐÔ¿ÆÑгɹû£º 3.1 ·¢ÏÖCD8+ Tϸ°û½éµ¼µÄË¥ÀÏÒÖÖÆ¼¹ËèËðÉËÐÞ¸´µÄлúÖÆ£¨Neuron, 2025£©£» 3.2 ½ÒʾÁËÖÜΧÉñ¾ËðÉËÏÂË¥ÀÏÒÖÖÆÉñ¾ËðÉ˺óÐÞ¸´µÄϸ°û½»»¥»úÖÆ£¨Science, 2022£©£» 3.3 ·¢ÏÖÁËÒÖÖÆ¸Ð¾õÉñ¾ÔªÖáÍ»ÔÙÉúµÄÖØÒª´úлµ÷¿Ø·Ö×Ó£¨Nature Metabolism, 2020£©¡£ 4. ½ü5Äê´ú±íÐÔÎÄÕ£º 1) Kong G, Song Y, Yan Y, Calderazzo SM, Saddala MS, De Labastida Rivera F, Cherry JD, Eckman N, Appel EA, Velenosi A, Swarup V, Kawaguchi R, Ng SS, Kwon BK, Gate D, Engwerda CR, Zhou L, Di Giovanni S. Clonally expanded targetable natural killer-like T cells seed the aged spinal cord to disrupt wound healing. Neuron 113£¬684-700 (2025). https://doi.org:10.1016/j.neuron.2024.12.012. 2) Yan Y, Antolin N, Zhou L, Xu L, Vargas IL, Gomez CD, Kong G, Palmisano I, Yang Y, Chadwick J, Muller F, Bull AMJ, Lo Celso C, Primiano G, Servidei S, Perrier JF, Bellardita C, Di Giovanni S. Macrophages excite muscle spindles with glutamate to bolster locomotion. Nature 637, 698-707 (2025). https://doi.org:10.1038/s41586-024-08272-5. 3) Palmisano I, Liu T, Gao W, Zhou L, Merkenschlager M, Mueller F, Chadwick J, Rivalta RT, Kong G, King JWD, Jibury EA, Yan YY, Carlino A, Collison B, De Vitis E, Gongala S, De Virgiliis F, Wang Z, Di Giovanni S. Three-dimensional chromatin mapping of sensory neurons reveals that promoter¨Cenhancer looping is required for axonal regeneration. P Natl Acad Sci USA 121 (2024). https://www.pnas.org/doi/full/10.1073/pnas.2402518121. 4) De Virgiliis F, Mueller F, Palmisano I, Chadwick JS, Luengo-Gutierrez L, Giarrizzo A, Yan Y, Danzi MC, Picon-Munoz C, Zhou L, Kong G, Serger E, Hutson TH, Maldonado-Lasuncion I, Song Y, Scheiermann C, Brancaccio M, Di Giovanni S. The circadian clock time tunes axonal regeneration. Cell Metab 35, 2153-2164 e2154 (2023). https://doi.org:10.1016/j.cmet.2023.10.012. 5) Muller F*, De Virgiliis F*, Kong G*, Zhou L*, Serger E, Chadwick J, Sanchez-Vassopoulos A, Singh AK, Eswaramoorthy M, Kundu TK, Di Giovanni S. CBP/p300 activation promotes axon growth, sprouting, and synaptic plasticity in chronic experimental spinal cord injury with severe disability. PLoS Biol 20, e3001310 (2022). https://doi.org:10.1371/journal.pbio.3001310. (Co-first author) 6) Serger E, Luengo-Gutierrez L, Chadwick JS, Kong G, Zhou L, Crawford G, Danzi MC, Myridakis A, Brandis A, Bello AT, Muller F, Sanchez-Vassopoulos A, De Virgiliis F, Liddell P, Dumas ME, Strid J, Mani S, Dodd D, Di Giovanni S. The gut metabolite indole-3 propionate promotes nerve regeneration and repair. Nature 607, 585-592 (2022). https://doi.org:10.1038/s41586-022-04884-x. 7) Zhou L*, Kong G*, Palmisano I, Cencioni MT, Danzi M, De Virgiliis F, Chadwick JS, Crawford G, Yu Z, De Winter F, Lemmon V, Bixby J, Puttagunta R, Verhaagen J, Pospori C, Lo Celso C, Strid J, Botto M, Di Giovanni S. Science 376, eabd5926 (2022). https://doi.org:10.1126/science.abd5926. (Co-first author) 8) Kong G, Zhou L, Freiwald A, Shkura K, Di Giovanni S. Purification of mouse axoplasmic proteins from dorsal root ganglia nerves for proteomics analysis. STAR Protoc 3, 101166 (2022). https://doi.org:10.1016/j.xpro.2022.101166. (Co-corresponding author) 9) Kong G, Zhou L, Serger E, Palmisano I, De Virgiliis F, Hutson TH, McLachlan E, Freiwald A, La Montanara P, Shkura K, Puttagunta R, Di Giovanni S. AMPK controls the axonal regenerative ability of dorsal root ganglia sensory neurons after spinal cord injury. Nat Metab 2, 918-933 (2020). https://doi.org:10.1038/s42255-020-0252-3. 10) La Montanara P, Hervera A, Baltussen LL, Hutson TH, Palmisano I, De Virgiliis F, Kong G, Chadwick J, Gao Y, Bartus K, Majid QA, Gorgoraptis N, Wong K, Downs J, Pizzorusso T, Ultanir SK, Leonard H, Yu H, Millar DS, Istvan N, Mazarakis ND, Di Giovanni S. Cyclin-dependent¨Clike kinase 5 is required for pain signaling in human sensory neurons and mouse models. Science Translation Medicine 12(2020). https://doi.org:ARTNeaax4860.1126/scitranslmed.aax4846 10.1126/scitranslmed.aax4846. |
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