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hanyanxiao89金虫 (小有名气)
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美国北德克萨斯大学University of North Texas 招博后和博士生
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The Han Lab at the University of North Texas is seeking a postdoctoral researcher to contribute to interdisciplinary research at the interface of molecular biophysics, hormone signaling, and therapeutic design. The primary focus of the lab is on G protein-coupled receptors (GPCRs), particularly those involved in cardiovascular and hormone signaling pathways. Using multiscale simulations—combining molecular dynamics, enhanced sampling, and kinetic modeling—the team investigates how neurotransmitters like norepinephrine and hormones such as estrogen interact with β-adrenergic and estrogen-related GPCRs. These studies aim to uncover the molecular basis of GPCR cross-talk and its impact on sex-specific cardiovascular function and disease. The lab is also interested in AI-driven design of peptides and proteins for therapeutic applications. This includes previously developed novel peptide drugs inspired by natural toxins to selectively target ion channels, as well as engineering antimicrobial peptides using machine learning and structural modeling approaches. This position offers an exciting opportunity to work on the mechanistic study of GPCR-mediated signaling, the rational design of next-generation biologics for precision medicine, and beyond. Degree Requirements Ph.D. in biophysics, computational biology, chemistry, pharmacology, or a related field Minimum Qualifications • Strong background in molecular dynamics simulations and/or protein modeling • Experience with enhanced sampling methods, multiscale modeling, and/or kinetic modeling is highly desirable • Interest in translational applications, including peptide/protein therapeutics or cardiovascular drug development • Experience mentoring students in a collaborative research environment Preferred Qualifications • Development and application of AI-driven methods in computational biomedical/biological related research • Experience collaborating with experimental (wet-lab) researchers • Strong verbal and written skills Application Materials • CV with contact information for three references • Research statement including future (or planned research projects) and past research. Contact • Please contact Dr. Yanxiao Han by email: Yanxiao.Han@unt.edu Job Duties: • Conduct funded research or self-driven related research • Write manuscripts, abstracts for conferences and attend scientific meetings • Write proposals for research projects • Provide informal mentoring to undergraduates and graduates associated with the lab 发自小木虫IOS客户端 |
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hanyanxiao89
金虫 (小有名气)
- 应助: 0 (幼儿园)
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- 虫号: 1796531
- 注册: 2012-05-05
- 专业: 生物大分子结构与功能
2楼2025-05-26 00:58:13
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