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澳大利亚莫纳什大学 — 英国纽卡斯尔大学联合博士项目
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澳大利亚莫纳什大学 — 英国纽卡斯尔大学联合博士项目招收1名2024年入学微生物及药理学专业全奖博士生 (奖学金为每年三万五澳元,约16.7万人民币) Monash University and Newcastle University (UK) Joint PhD Project Project description: Our project addresses the urgent issue of antimicrobial resistance (AMR) which poses a significant threat to global public health. This threat was highlighted in 2017 when the WHO released its first-ever priority pathogen list of notorious antibiotic-resistant bacteria, designating Pseudomonas aeruginosa as a ‘Critical’ pathogen. In this PhD project, we aim to establish in vitro host-pathogen-antibiotic tripartite models (e.g., the 3D organotypic model of the human airway) to investigate antibiotic-induced metabolic perturbations in the host microenvironment during P. aeruginosa infection. Notably, essential metabolite biomarkers that modulate antibiotic efficacy will be identified, with the aim of enhancing the treatment effectiveness against P. aeruginosa. This research will provide novel mechanistic insights to optimise antibiotic use in clinical settings and combat multidrug-resistant bacterial infections. This is a joint PhD project between Monash and Newcastle Universities, supervised by a multidisciplinary research team. The project will employ cutting-edge technologies such as quantitative metabolomics and MALDI-MS imaging to elucidate the complex metabolic interplay between bacteria and the host microenvironment in 3D organotypic infection models. The candidate will conduct experiments and gain expertise in the co-supervisors' respective areas in their well-equipped laboratories at Monash and Newcastle Universities. The candidate will also benefit from the excellent research environments and support at both institutions. Home Institution: Monash University (AU); Dr Meiling Han and Prof Jian Li (https://www.monash.edu/discovery ... ments/microbiology) Host Institution: Newcastle University (UK); Drs Chien-Yi Chang and Christopher Nile (https://www.ncl.ac.uk/dental/res ... l-oral-biosciences) PhD Duration: up to 3.5 years including 2.5 years in Monash and 1 year in Newcastle. Stipend Scholarship: ~AU$ 35,000 annually with waived tuition fee Candidate requirement: Masters’ or honours graduates (H1A, 2:1+, or equivalent) with a background in Pharmacology, Microbiology or Analytical Chemistry. Contact: Please send your CV and transcripts to: Dr Meiling Han; email: meiling.han@monash.edu; phone: +61 (3) 990 29129; https://research.monash.edu/en/persons/meiling-han 【申请要求】 1. 化学,药学,微生物学等相关专业硕士学历 2. 已发表至少一篇jcr 1区sci文章,且本科及硕士GPA不低于3.2 3. 具备良好的英文沟通和阅读写作能力,雅思总分不低于6.5(单科成绩不低于6.0) 【学校简介】 莫纳什大学是位于澳大利亚维多利亚州墨尔本市的一所研究型综合大学,建校于1958年,是澳洲八大名校成员,世界百强名校。莫纳什大学于世界大学排名中,一直位处前列,是澳洲顶尖的研究型大学之一。 2024年,莫纳什大学于QS世界大学排名第37位,泰晤士高等教育世界大学排名第54位(澳洲第二位)。莫纳什大学生命科学与医学相关专业更是走在世界的前列,其中药学与药剂学专业在2024年QS世界大学学科排名中位列世界第二。 纽卡斯尔大学(英语:Newcastle University),是位于英格兰东北部泰恩河畔纽卡素的国立研究型大学,为英国罗素大学集团成员之一。该校创建于1834年, 并于在1837年被授予皇家宪章,定名纽卡素大学。创建之初名为“医学与外科学院”(School of Medicine and Surgery),随后成为分裂改制前的杜伦大学的另一半部的学院,在1963年根据国会法案(Act of Parliament)与杜伦大学分别成立各自独立的学校,正式全名为“泰恩河畔纽卡素大学”(University of Newcastle upon Tyne)。 纽卡素大学以拥有欧洲最顶尖的医学院著称。该校无论在医学、科学及人文等方面皆相当著名,同时,该校也是英国拥有最多的欧盟研究文件的学校之一。 请有申请意向的同学尽快将个人CV和成绩单发送至meiling.han@monash.edu |
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