| 查看: 125 | 回复: 1 | |||
| 当前主题已经存档。 | |||
[交流]
帮忙看下如何反应
|
|||
|
An antibacterial fluoroquinolone enoxacin enhanced RNA interference (RNAi) Although major protein components of the RNA interference (RNAi) pathway have been identified, regulatory mechanisms of gene expression for the RNAi pathway remain largely unknown. Here, Shan et al. have reported a small molecule antibacterial fluoroquinolone enoxacin enhanced RNAi, and its basic principle. To monitor the activity of the RNAi, they developed a stable cell line (RNAi-293-EGFP)-based green fluorescence detection system. The cell line was prepared from human cell (293-EGFP), expressing gene encoding enhanced green fluorescent protein (EGFP), and was infected with a lentivirus expressing a short hairpin RNA (shRNA) targeting EGFP mRNA. Using this system, they identified enoxacin increased EGFP gene knockdown mediated by siRNA against EGFP in a dose-dependent manner. They showed that enoxacin could facilitate the interaction between trans-activation-responsive region RNA-binding protein and RNAs. 各位学生物的，麻烦看看这段话符合反应，我学有机的，实在不能理解。太纠结了。 |
回复此楼» 猜你喜欢
什么是人一生最重要的？
已经有6人回复
-
为什么中国大学工科教授们水了那么多所谓的顶会顶刊，但还是做不出宇树机器人？
已经有11人回复
-
网上报道青年教师午睡中猝死、熬夜猝死的越来越多，主要哪些原因引起的？
已经有9人回复
-
【博士招生】太原理工大学2026化工博士
已经有5人回复
-
280求调剂
已经有3人回复
-
面上可以超过30页吧？
已经有11人回复
-
版面费该交吗
已经有15人回复
-
体制内长辈说体制内绝大部分一辈子在底层，如同你们一样大部分普通教师忙且收入低
已经有18人回复
2楼2009-10-15 15:02:50