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密西根韦恩州立诚招2024博士生 - 内耳细胞生物学生物力学方向
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About 9% of adults aged 55 to 64 have disabling hearing loss. The most common cause of hearing loss is cochlear damage. The human cochlea converts sounds into neural impulses. The sensory structure for sound in the cochlea – the organ of Corti – comprises a variety of cells that are essential for hearing and extremely susceptible to loud noises, drugs, and aging. How these cells individually contribute to hearing is not fully understood. How their forms and functions are affected by noise exposure or aging is unclear. Our lab aims to elucidate the roles of individual cells in the organ of Corti for sound transmission and study their morphological and functional changes in damaged cochleae. We use cutting-edge optical technologies to measure the shapes, mechanical properties, and motions of these cells. We develop computational models to gain insights into the role of each cell in cochlear sound transmission. Our long term goal is to understand the mechanism underlying the cochlear hearing loss and devise new therapeutics to restore hearing. We are recruiting two PhD students with background in Biology, Biomedical Engineering, Chemistry, Biochemistry, Applied Physics, Optical Engineering, or Hearing Science. Our lab is located at the Integrative Biosciences Center (IBio) at Wayne State University (https://ibio.wayne.edu/). The lab has expertise in acoustic and biomechanical aspects of the middle ear and the cochlea. Our recent publications can be found here: https://www.ncbi.nlm.nih.gov/myncbi/xiying.guan.1/bibliography/public/ The tuition of the PhD program and the cost of living in our university are about $40,000 per year. Depending on the strength of the applicant, a scholarship of $28,000/year or $40,000/year will be awarded to the applicant upon admission. To apply, please email (1) cover letter describing research experience & interests, (2) transcripts and (3) CV to Dr. Xiying Guan (xiying_guan@wayne.edu). Please include "2024 PhD" in the title of your email. |
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