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Anton (Tony) J. Hopfinger, Distinguished Research Professor of Pharmacy, University of New Mexico, Professor Emeritus of Medicinal Chemistry and Pharmacognosy, University of Illinois, and co-Founder and Chief Science Officer of The Chem21 Group, Inc. is the recipient of the 2010 Herman Skolnik Award presented by the ACS Division of Chemical Information (CINF). The award recognizes outstanding contributions to and achievements in the theory and practice of chemical information science and related disciplines. The prize consists of a $3,000 honorarium and a plaque.

Tony Hopfinger is recognized as a pioneer and major contributor in the fields of quantitative structure activity relationship (QSAR) and quantitative structure property relationship (QSPR) techniques employing three and higher dimensional levels of information derived from modeling and simulation. Tony has addressed chemical information and modeling problems in the pharmaceutical, polymer and materials sciences, in both industry and academia, and he is generally acknowledged as having fathered the development of QSPR modeling in polymer and materials science, including coining the acronym QSPR. The breadth of his interests and the applicability of the techniques he has developed are reflected in the topics covered in some of his recent papers, including drug discovery, ADME-Tox property prediction, nanotoxicity, cheminformatic descriptors and molecular similarity analysis.

Tony has made many contributions to the field of cheminformatics through publication, teaching, mentoring, advising and organizing. He has authored or co-authored more than 270 peer-reviewed (and highly cited) papers and delivered almost 360 invited lectures. He has served on many journal editorial boards and has been an associate editor the Journal of Chemical Information and Modeling (previously Journal of Chemical Information and Computer Science) for the past 16 years. He has been a member of government and industrial advisory boards, and he chaired a Gordon Research Conference on Quantitative Structure Activity-Relationships in Biology. He has coordinated and taught at short courses in North and South America and Europe; more than 50 computational scientists earned their Ph.D. degrees under Tonys mentoring; and he has also provided advanced training to more than 70 postdoctoral students.

Tony Hopfinger received a B.S. in Math and Physics from the University of Wisconsin in 1966, and a Ph.D. in Biophysical Chemistry from Case Western Reserve University in 1969. He started his career in 1969 as an NIH Postdoctoral Fellow, Department of Biological Chemistry, Harvard Medical School, and from there moved to Case Western Reserve University in 1970 as Assistant Professor of Macromolecular Science. He held increasingly senior positions at Case Western, eventually becoming Professor of Macromolecular Science in 1978 and Director, Research Computing Laboratory in 1979. In 1981 he moved from academia to industry, joining G.D. Searle (now part of Pfizer) as Director, Department of Drug Design, and later Director, Department of Medicinal Chemistry. Tony maintained links with academia, holding several adjunct and visiting professorships, and in his spare time founded, or co-founded, a number of software and pharmaceutical companies including Intersoft, ChemLab, Receptor L!
aboratories and DNACodes. He returned to academia in 1985 and was Professor of Bioengineering, Chemistry and Medicinal Chemistry, University of Illinois at Chicago until 2005. Since then he divides his time as Distinguished Research Professor of Pharmacy, University of New Mexico, Chief Science Officer of The Chem21 Group, Inc.  and Professor Emeritus of Medicinal Chemistry and Pharmacognosy, University of Illinois.

Tony Hopfinger is highly respected by all of his colleagues worldwide and this Award is a well-deserved recognition of the outstanding career of an unstinting and generous pioneer and practitioner of cheminformatics.  

Phil McHale
Chair, CINF Awards Committee

[ Last edited by zdhlover on 2009-11-14 at 15:39 ]
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