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[交流] PhD Project——University of South Australia

PhD Project - Towards Precision Cancer Radiotherapy through Patient-Derived Tumour on-Chips Reconstructing the Tumour Microenvironment

If you are seeking to advance your career in bioengineering and are interested in cancer treatment research, the University of South Australia – Australia’s University of Enterprise – is offering a prestigious project-based PhD in the Future Industries Institute in partnership with the Department of Radiation Oncology at the Royal Adelaide Hospital.

Supervisory Team
Dr Chih-Tsung Yang- Principal Supervisor
Professor Benjamin Thierry - Co-Supervisor
Dr Nicole Dmochowska – Co-Supervisor
Associate Professor Hien Le (Royal Adelaide Hospital)
Mr Stewart Bartlett (Ferronova)

具体信息请见链接:
https://workingatunisa.nga.net.a ... ienceTypeLanguage=1


请发送简历至:Dr. Chih-Tsung Yang
Email: Chih-Tsung.Yang@unisa.edu.au

Prof. Benjamin Thierry
Email: benjamin.thierry@unisa.edu.au
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dndxgzb

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链接网页中的详细信息(如果网页打不开的话):

Towards Precision Cancer Radiotherapy through Patient-Derived Tumour on-Chips Reconstructing the Tumour Microenvironment
PhD Project - Towards Precision Cancer Radiotherapy through Patient-Derived Tumour on-Chips Reconstructing the Tumour Microenvironment

Develop a precision radiotherapy tool to assist with cancer treatment

If you are seeking to advance your career in bioengineering and are interested in cancer treatment research, the University of South Australia – Australia’s University of Enterprise – is offering a prestigious project-based PhD in the Future Industries Institute in partnership with the Department of Radiation Oncology at the Royal Adelaide Hospital.

There is a critical need for practice redefining radiotherapy advances that balance the efficacy of the treatment with survivors’ quality of life. Building on an existing collaboration between UniSA, the Royal Adelaide Hospital and Harvard University, this PhD project will create a precision radiotherapy tool designed to guide the selection of the optimal radiotherapy plan for a specific cancer patient.

To realise this goal, the project will develop and utilise a bioengineered tumour model that reconstruct the main pathophysiological characteristics of tumour tissues, and therefore that shed new insight in the complex relationship between the phenotype of a patient tumour (including its tumour microenvironment) and its response to specific radiotherapy algorithms. This advanced patient-derived tumours on chip will be compatible with modern radiotherapy technology including highly hypofractionated approaches and proton beam therapy. The insight gained through these studies will guide the design of precision radiotherapy for cancer patients.

This PhD project is highly inter-disciplinary, bringing together bioengineering, cancer biology and transcriptomics, and will provide you with exciting learning opportunities.

You will be primarily based at the Future Industries Institute’s (FII) bioengineering lab, which is fully equipped with cell and organoid culture facilities. You will also work in the Australian National Fabrication Facilities to design and fabricate devices for patient-derived organoid culture. In addition, the FII is equipped with state-of-art analytical and imaging instruments for cellular and molecular biology.

This project will also provide you with the opportunity to work in the state-of-art proton beam therapy facility at the Australian Bragg Centre for Proton Therapy and Research. This is your opportunity to undertake cutting edge, end-user driven research in collaboration with world-class research organisations.

What you’ll do

In this PhD project, you will conduct high quality research independently and in collaboration with the supervisory team, our industry partners and other stakeholders. You will apply bioengineering concepts to develop a patient-derived tumour organoid model and apply this model to gain insight into the links between tumour phenotypes and radioresponsivity.

This project will provide you with valuable opportunities to collaborate with radiation oncologists, pathologists and bioinformaticists. You will receive advanced training in organs-on-chip technology and single-cell transcriptomics and apply this training throughout the project.

You will contribute to patent application(s) protecting the intellectual property of the project and help prepare human research ethics applications.

Through this project you will present your research at international and national conferences and via publications via scientific journals, which will help you build an extensive professional network. A travel allowance from the Future Industries Institute is available to support these activities.

Upon completion, you will possess valuable soft skills such as high-level thinking and problem-solving, managing cross-disciplinary research teams, including end-users, and communicating research outcomes and managing intellectual properties. You will also build practical skills and expertise in in vitro tumour models and precision radiotherapy and preclinical research.

There may also be opportunities for you to benefit from placements with our project collaborators, such as the Royal Adelaide Hospital, and Harvard University’s Dana Farber Cancer Institute.

Where you’ll be based

You will be based in the Future Industries Institute (FII) which was established with a new research culture in mind – one deeply engaged with industry, with the end goal of building economic growth through relevant innovation and industry partnership.

The Institute reflects the University’s strategic ambition to be Australia’s University of Enterprise which engages fully with the professions and industry globally, whose research is informed, leading edge and relevant. The FII continues to forge national and international research partnerships in new industries and technologies that address real world issues. Our goal is to support a creative and engaged culture and to help develop a sustainable ecosytem in which innovation, complex, growth-focused industries thrive.

The FII's research supports state and national research priorities and comprises of top research teams that collaborate across disciplines and to work with industry partners to deliver innovative solutions.

With a vibrant research environment, a strong industry orientation, and active international and national links, both academic and industry based, the Institute is among the very best in Australia and attracts and retains leading researchers.

Supervisory Team
Dr Chih-Tsung Yang- Principal Supervisor
Professor Benjamin Thierry - Co-Supervisor
Dr Nicole Dmochowska – Co-Supervisor
Associate Professor Hien Le (Royal Adelaide Hospital)
Mr Stewart Bartlett (Ferronova)

Financial Support

This project is funded for reasonable research expenses.  Additionally, a living allowance scholarship of $28,854 per annum is available to eligible applicants. A fee-offset or waiver for the standard term of the program is also included. For full terms and benefits of the scholarship please refer to our scholarship information for domestic students or international students.

Eligibility and Selection

This project is open to application from both domestic and international applicants.

Applicants must meet the eligibility criteria for entrance into a PhD degree. All applications that meet the eligibility and selection criteria will be considered for this project. A merit selection process will be used to determine the successful candidate.

The successful applicant is expected to study full-time and to be based at our Mawson Lakes Campus in the north of Adelaide.  Additionally, applications from students studying externally will also be considered.  Note that international students on a student visa will need to study full-time.

Essential Dates

Applicants are expected to start in a timely fashion upon receipt of an offer.  Extended deferral periods are not available.  Applications close on Wednesday, 8th June.
2楼2022-05-11 15:09:04
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dndxgzb

金虫 (初入文坛)

引用回帖:
2楼: Originally posted by dndxgzb at 2022-05-11 15:09:04
链接网页中的详细信息(如果网页打不开的话):

Towards Precision Cancer Radiotherapy through Patient-Derived Tumour on-Chips Reconstructing the Tumour Microenvironment
PhD Project - Towards Precisi ...

3楼2022-05-23 15:59:55
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dndxgzb

金虫 (初入文坛)

4楼2022-05-23 16:30:23
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Forever晶

新虫 (初入文坛)

5楼2022-05-23 17:11:06
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dndxgzb

金虫 (初入文坛)

引用回帖:
5楼: Originally posted by Forever晶 at 2022-05-23 17:11:06
基础医学可以吗

请发送简历至:Dr. Chih-Tsung Yang
Email: Chih-Tsung.Yang@unisa.edu.au

或者 Prof. Benjamin Thierry
Email: benjamin.thierry@unisa.edu.au

两位导师会进行评估并给您回复。
6楼2022-05-24 14:39:12
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