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[资源] 【分享】Cambridge新书： Protein Interaction Networks: Computational Analysis

Paperback: 292 pages
Publisher: Cambridge University Press; 1 edition (April 6, 2009)
Language: English
ISBN-10: 0521888956
ISBN-13: 978-0521888950
Format: PDF

Description: The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions. Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks. The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation. This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks. It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods. The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.

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Protein Interaction Networks: Computational Analysis

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