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南洋理工大学Sing Yian CHEW教授招聘组织工程方向（材料）博士后
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博士后/研究员职位 3D打印和支架设计用于组织工程中药物/基因递送 南洋理工大学 化学与生物医学工程学院 李光前医学院 https://personal.ntu.edu.sg/sychew 新加坡南洋理工大学的Sing Yian CHEW教授实验室招聘组织工程、支架设计和药物/基因递送研究方向的博士后/研究员。 该研究项目的重点是设计组织支架，实现表面拓扑结构的构建和进行可持续的药物/基因递送，从而介导细胞响应和神经组织再生。目前实验室亟需对相关领域感兴趣的人员，从事以下工作：设计、3D打印和表征新型可生物降解、可生物相容的组织支架，实现可控的药物/基因递送以介导细胞响应和神经组织再生；表征支架和细胞/组织的相互作用；研究相关影响因素，以控制药物/基因递送和支架降解的速率和程度。 实验室通过与海内外多个学术机构的紧密合作，致力于将组织支架工程和可控的药物/基因递送系统应用于神经组织工程和干细胞工程。 主要岗位职责： • 设计和表征具有可控药物递送能力的新型可生物降解、可生物相容的材料和组织支架，用于神经组织工程和干细胞工程。 • 设计、优化和制造组织支架（例如：水凝胶、可注射支架、静电纺丝、3D打印）。 • 表征支架特性：物理特性、药物/基因释放动力学、细胞/组织相互作用等。 • 独立设计和进行实验。 • 希望能够分析实验结果，并在相关领域的高质量期刊发表论文。 • 有优秀的沟通能力，并对科学充满热情和奉献精神。 • 与PI紧密合作，帮助监督和培训实验室新成员，并确保研究计划积极、顺利地进行。 • 能在相互协作的环境中工作。 • 候选者将有机会跨职能去探索自己的研究兴趣。 要求： • 具有博士学位，具备相关研究背景和学术经验。 • 在生物材料支架设计、制造和表征，以及可控药物/基因递送的设计和表征方面发表过论文。掌握蛋白质印迹、免疫染色、qPCR、荧光显微镜（共聚焦）成像等实验技能，以分析评估支架的细胞反应/相互作用/功能。 • 具有3D打印经验者优先。 • 有较强的口语和写作能力。 • 可独立开展研究工作。 • 具有较强的组织能力和主动性，具有积极性、创造性、批判性和分析性思维，较强的科学责任感和团队合作能力。 该职位的招聘申请将持续进行，直到名额招满为止。申请人需要提交求职信，说明感兴趣的领域以及初步的研究计划。另外附一份完整的简历和三份推荐信。请将申请材料发至Sing Yian CHEW博士邮箱：sychew@ntu.edu.sg Postdoc/Research Fellow position in 3D-printing & Scaffold Design for Drug/gene delivery in Tissue Engineering Nanyang Technological University School of Chemical & Biomedical Engineering Lee Kong Chian School of Medicine https://personal.ntu.edu.sg/sychew A Postdoc/Research Fellow position is available in the laboratory of Dr. Sing Yian CHEW at Nanyang Technological University, Singapore, to a highly motivated candidate who has a passion for tissue engineering, scaffold design and drug/gene delivery research. The focus of this project is to design tissue scaffolds to impart topographical signals and sustained drug/gene delivery to direct cell fate and neural tissue regeneration. We are seeking an individual who is interested in designing, 3D-printing and characterizing novel biodegradable, biocompatible tissue scaffolds with controlled drug/ gene delivery capabilities to direct cell response and neural tissue regeneration, characterizing scaffold-cell/tissue interactions, engineering factors that control the rate and extent of drug/gene delivery and scaffold degradation. This position offers a unique opportunity to apply tissue scaffold engineering and controlled drug/gene delivery skills to neural tissue engineering and stem cell engineering, through strong collaborative efforts with multiple local and overseas academic institutes. Key responsibilities: • Design and characterize novel biodegradable, biocompatible materials and tissue scaffolds with controlled drug delivery capabilities for neural tissue engineering & stem cell engineering. • Design, optimize and fabricate tissue scaffolds (e.g. hydrogels, injectable scaffolds, electrospinning, 3D printing) • Characterize scaffold properties: physical characteristics, drug/gene release kinetics, cell/tissue interactions, etc. • Design and execute experiments independently. • Expected to interpret experimental results, and author papers in high-quality journals in areas that are related to the research. • Demonstrate excellent communication skills and have a strong passion and commitment to science. • Work closely with the Principal Investigator to help supervise and train junior lab members and to ensure smooth functioning of an active research program. • Expected to work in a collaborative inter-institute environment. • The candidate will have the opportunity to explore his/her own interests across functions. Requirements: • Ph.D. level scientist with relevant background and experience. • Published experience in biomaterials scaffold design, fabrication and characterization, controlled drug/gene delivery design and characterization. Evaluation of cellular response/interactions/functionality with scaffolds using western blotting, immunostaining, qPCR, fluorescent microscopy (confocal) imaging, functional assays. • Experience in 3D printing is a plus. • Strong ability to communicate effectively orally and in written form. • Strong ability to perform independent, self-directed work. • Strong organizational skills and proactive personality with outstanding motivation, creativity, critical and analytical thinking skills, strong scientific commitment and ability to work as a team. Review of applicants will continue until position is filled. Applicants should submit a cover letter indicating their area of interest and how they intend to participate and contribute to the research, complete curriculum vitae and addresses of three references to Dr. Sing Yian CHEW: sychew@ntu.edu.sg. Only short-listed candidates will be contacted. |
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