| 查看: 528 | 回复: 0 | |||
[交流]
POSTDOCTORAL POSITION IN NEUROSCIENCE
|
|
The Song Lab at University of Pennsylvania/Children’s Hospital of Philadelphia is seeking creative and dedicated individuals with a strong passion for research, curiosity and self-motivation. Our lab offers an exciting opportunity to work in a closely collaborative, inspiring and dynamic environment. The long-term goal of the Song lab is to elucidate the cellular and molecular basis governing the formation, maintenance and function of neural circuits under physiological and pathological conditions. We are particularly interested in understanding how nervous system copes with injury and are developing strategies to promote neuroregeneration. We have established Drosophila injury models, are performing genetic screens to identify pathways regulating regeneration, are testing the evolutionary conservation of the novel regeneration regulators combining with mammalian injury models, and focus on targeting both the intrinsic and extrinsic mechanisms. With a background in neural development, neural circuits and behavior, fly and mouse genetics, injury and neurodegeneration, and tumor models, our lab offers a unique skillset to achieve this goal. Our lab is focused on three main themes: 1. Elucidating the mechanisms underlying neural degeneration and regeneration 2. Developing fly models for studying human neurodevelopmental disorders 3. Developing fly models for studying tumorigenesis Visit our lab website for more details https://songlab.research.chop.edu. Here is a shortlist of our recent publications: 1. Li D*#, Wang Q*, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Sacoto MJG, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala S, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y#, Hakonarson A. Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. Science Advances 2021 In press. #Co-corresponding authors. 2. Li F, Sami A, Noristani HN, Slattery K, Qiu J, Groves T, Wang S, Veerasammy K, Chen YX, Morales J, Hanes P, Sehgal A, He Y, Li S#, and Song Y#. Glial metabolic reprograming promotes axon regeneration and functional recovery in the central nervous system. Cell Metabolism 32(5): 767-785, November 2020. 3. Wang Q, Fan H, Li F, Sharum SR, Krishnamurthy V, Song Y#, Zhang K#. Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila. eLife 9, October 2020. #Co-corresponding authors. 4. Muir AM, Cohen JL, Sheppard SE, Guttipatti P, Lo TY, Weed N, Doherty D, Fagerberg C, Kjærsgaard L, Larsen MJ, Wemmenhove-Lohner K, Hirsh Y, Zeevi DA, Zackai EH, Bhoj E, Song Y#, Mefford HC#. Bi-allelic Loss-of- Function Variants in NUP188 Cause a Recognizable Syndrome Characterized by Neurologic, Ocular, and Cardiaac Abnormalities. Am J Hum Genet. 106(5): 623-631, May 2020. #Co-corresponding authors. 5. Monahan Vargas EJ*, Matamoros AJ*, Qiu J*, Jan CH, Wang Q, Gorczyca D, Han TW, Weissman JS, Jan YN, Banerjee S and Song Y. The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration. Genes and Development 34(3-4): 194-208, February 2020. 6. Song Y#, Li D, Farrelly O, Miles L, Li F, Kim SE, Lo TY, Wang F, Li T, Thompson-Peer KL, Gong J, Murthy SE, Coste B, Yakubovich N, Patapoutian A, Yang X, Rompolas P, Jan LY, Jan YN#. The mechanosensitive ion channel Piezo inhibits axon regeneration. Neuron 102(2): 373-389, February 2019. #Co-corresponding authors. Successful candidates will benefit from the thriving and collegial UPenn/CHOP research community, tailored career development guidance, state-of-the-art research facilities and excellent benefits packages. Applicants should have a PhD and/or MD degree, and background in fly genetics, mammalian injury models or bioinformatics is highly recommended. Prospective applicants should send a brief statement of research, CV and the names and contact information of three references to Yuanquan Song at songy2@chop.edu. It is your accomplishment that leads to the success of the lab! Yuanquan Song, Ph.D. Assistant Professor, Department of Pathology & Laboratory Medicine Perelman School of Medicine, University of Pennsylvania The Raymond G. Perelman Center for Cellular and Molecular Therapeutics The Children's Hospital of Philadelphia Philadelphia, PA 19104 songy2@chop.edu |
回复此楼» 猜你喜欢
面上再次挂了，太难了，躺也躺不了，倦也卷不过，小学校之殇！
已经有22人回复
-
2026年国自然面上资助率
已经有19人回复
-
微信指数没变化，科研之友没阅读
已经有18人回复
-
基础研究怎么拉横向，学校到款任务越来越多，难以完成 拉横向，都有哪些途径啊
已经有8人回复
-
HXDI做水性聚氨酯乳液，是不是特别容易出渣
已经有3人回复
-
系统今天又提示维护了，估计离放榜不远了
已经有15人回复
-
你们的时间戳变了吗
已经有4人回复
-
今年的WR进展到哪一步了？
已经有9人回复
-
产物和副产物价值比较
已经有5人回复
-
时间戳他又来了
已经有17人回复