| 查看: 944 | 回复: 0 | |||
zyy蓝心新虫 (初入文坛)
|
[交流]
2021 招收 CSC PhD (PSL-ChimieParistech)
|
|
2021 招收 CSC PhD (PSL-ChimieParistech) Field: Chemistry, Physical Chemistry and Chemical Engineering, Life Science and Engineering for Agriculture, Food and the Environment Subfield: Electrochemistry, Bio analytical chemistry Title: Hydrogel Matrix Grafted electrochemical Aptasensors for the Detection of emerging pollutants ParisTech School: Chimie ParisTech Advisors Name: Cyrine Slim, Sophie Griveau, Fethi Bedioui Advisors Email: Cyrine.slim@chimieparistech.psl.eu/sophie.griveau@chimieparistech.psl.eu Research group/Lab: Institute of Chemistry for Life and Health Sciences, i-CLeHS Lab location : ENSCP Chimie Paristech 11, rue Pierre et Marie Curie 75231 Paris Cedex 05, France Lab website: https://iclehs.fr/research/seisad/ Short description of possible research topics for a PhD: Driven by the growing concern about the release of the untreated emerging pollutants and the urgent demand of determining low level of these pollutants present in environment, novel biosensors dedicated to molecular recognition will be developed. The objective of the project is to design biosensors using a novel class of grafted polymers, surface-attached hydrogel thin films on conductive transducer as biocompatible matrix for biomolecule immobilization. From biomolecules, aptamers constitute an attractive alternative to antibodies due to their high affinity and their excellent specificity for a target or a family of selected targets. It is also possible to functionalize them with specific chemical functions and/or with tag to label the aptamers, for their further immobilization and/or for their analysis. The immobilization of the aptamer onto surface-attached hydrogel thin films by covalent attachment provides a biodegradable shelter, providing the aptamer excellent environments to preserve its active and functional structure while allowing the detection of pollutants. For improved sensitivity and higher stability of the sensor, a high density of immobilized aptamer is enabled. Within a constant miniaturization effort, we will tend towards the transposition of this work, towards microfluidic electrochemical biosensors on real samples due to their miniature, portable and low-cost systems as well as high through put and automation. The integration of electrochemical sensors into microfluidic formats with the incorporation of unique materials for detection will be explored in this project. The development of these systems would lead to significant advantages compared to the current analytic systems, in terms of simplicity, speediness, cost, and automation. Required background of the student: Physical chemistry, ideally background in basic electrochemistry If you are interested in this projects, please contact Cyrine Slim, Sophie Griveau, 或者可以留帖给我。 |
回复此楼» 猜你喜欢
梦想
已经有7人回复
-
学科评审组评审是指会评吗？
已经有4人回复
-
面上合作单位盖章
已经有8人回复
-
面上函评意见出来了，像什么等级？
已经有15人回复
-
为什么资助数各大高校都创新高，自己申请怎么就这么难
已经有14人回复
-
小白求助 投论文要求的highlights应该如何写
已经有4人回复
-
麻烦专家们看看评委们的意见（F口面上）
已经有12人回复
-
怎么看青基中了没有啊
已经有6人回复
-
国社科又开始会评了，不知道这次命运如何
已经有11人回复
-
有多少人是今天查系统知道结果的？
已经有19人回复
20