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To help authors provide actual size graphics, it is suggested that the following settings be used with CSC ChemDraw and ISIS Draw: font 10 pt Helvetica, chain angle 120¡ã, bond spacing 18% of length, fixed length 10.08 pt (0.354 cm), bold width 1.4 pt (0.049 cm), line width 0.42 pt (0.015 cm), margin width 1.12 pt (0.040 cm), and hash spacing 1.75 pt (0.062 cm). Compound numbers should be in boldface. In order to accurately design schematics to print out at the proper width, the original drawing cannot exceed a column width of 8.8 cm (for single column) and 18.3 cm (for double column). Layout design is facilitated if authors submit their original artwork in the actual size to be published. Please save graphics as an Encapsulated PostScript file (EPS) or a Tagged Image File Format (TIFF), as well as the program the graphic was originally drawn in. For more details on the preparation and submission of artwork, please visit www.elsevier.com/artworkinstructions.
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