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[交流] 药动学参数的达峰时间Tmax为什么由中位数描述？

药动学参数的达峰时间Tmax为什么由中位数描述？
而其它的参数如Cmax则用均值±SD描述。
求问，谢谢大家

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1楼 2020-02-10 19:45:09

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the tmax variable is a categorical variable that can only take values based on the planned sampling scheme. Thus if your planned sample schedule includes 0, 1, 2, 4, 6, and 8 hours, you cannot have a sample at 1.5 or 10 hours (unless there was a deviation). Thus the expected values for tmax are confined to some pre-selected categories. Thus when you summarize tmax results, you should NOT use averages and standard deviations, as they do not accurately describe the distribution of values. Instead, you should use medians and ranges. The median is the “middle” of the data, and the range represents the “extremes” of the data.

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6楼2020-03-01 22:23:09

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6楼: Originally posted by 575526368 at 2020-03-01 22:23:09
the tmax variable is a categorical variable that can only take values based on the planned sampling scheme. Thus if your planned sample schedule includes 0, 1, 2, 4, 6, and 8 hours, you cannot have a ...

这是哪本书里面的啊?能不能提供一下，谢谢

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7楼2020-03-14 21:55:15

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