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We are now having opening for PhD students from a variety of backgrounds (mechanical engineering, chemical engineering, biomedical engineering, chemistry, biology). Candidates with cell culture, nanotechnology, or microfabrication will be highly preferred.

Our lab is focusing on leveraging micro/nanotechnology for investigation of mechanobiology. We have particular interest in cell’s left-right bias, e.g. rightward biased migration, rotation, and orientation. We recently discovered that cells can generate a torque with rotational bias depending on cell types. As a leading group in such rotational mechanics, our research provides a fundamental framework in guiding cell mechanics, stem cell differentiation, and tissue regeneration. Some related publications can be found below:

Wei Liu, Yuanye Bao, Miu Ling Lam, Ting Xu, Kai Xie, Hin Sum Man, Edward Y. Chan, Ninghao Zhu, Raymond H. W. Lam, and Ting-Hsuan Chen*, Nanowire Magnetoscope Reveals a Cellular Torque with Left-Right Bias, ACS Nano, vol. 10(8), pp. 7409 - 7417, 2016
Yuanye Bao, Yaozhun Huang, Miu Ling Lam*, Ting Xu, Ninghao Zhu, Zhaobin Guo, Xin Cui, Raymond H. W. Lam and Ting-Hsuan Chen*, Substrate Stiffness Regulates the Development of Left-Right Asymmetry in Cell Orientation, ACS Applied Materials & Interfaces, vol. 8(28), pp. 17976 - 17986, 2016

In addition, We are also interested in development of biosensors based on nanotechnology and DNA nanomachines. That is to detect biomarkers in live cells or microfluidics assays for portable biosensors. Some related publications can be found below:

Zichen Zhao, Yuanye Bao, Lok Ting Chu, John Kin Lim Ho, Ching-Chang Chieng, and Ting-Hsuan Chen*, Microfluidic Bead Trap as a Visual Bar for Quantitative Detection of Oligonucleotides, Lab on a Chip, 2017
Shan Chen, Lok Ting Chu, and Ting-Hsuan Chen*, Colorimetric Detection of Active Botulinum Neurotoxin Using Cu2+ Mediated Gold Nanoparticles Agglomeration, Sensors and Actuators B: Chemical, vol. 235, pp. 563-567, 2016
Shan Chen, Lok Ting Chu, Pak Piu Yeung, Zichen Zhao, Bao Yuanye, Miu Shan Chan, Pik Kwan Lo and Ting-Hsuan Chen*, Enzyme-Free Amplification by Nano-'Sticky Balls' for Visual Detection of ssDNA/RNA Oligonucleotides, ACS Applied Materials & Interfaces, vol. 7(41), pp. 22821-30, 2015

Monthly studentship: HKD 17,000
Regular study period in City U: 4 years

We are open to inquiries regarding the interests of joining our group. If interested, please send you CV and also include the transcripts and English test result (TOEFL, IELTS, or CET-6). T
he inquiry should be addressed to: thchen@cityu.edu.hk.

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