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[求助]
实验性肺转移模型注射癌细胞前用制剂预孵育的原因
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最近看到一篇文献中：Antimetastatic Activity in Experimental Lung Metastasis Model. Five-week old female Balb/c mice were assigned into 14 groups (n = 5). Five ×105 4T1 cells were pretreated with AMD3100(1 mM), and polyplexes (w/w 4) for 4 h before i.v. injection in 100μL PBS (Day 1). The animals were then treated i.v. with AMD3100(1.25 mg/kg) and polyplexes (1.2 mg/kg siScr) on day 3, 5, 7, and 9 and sacrificed on day 11. 请问这里为什么在尾静脉注射4T1细胞建立肺转移模型之前用制剂进行预孵育，有什么好处，求助！ |
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