| 查看: 588 | 回复: 6 | ||
| 【奖励】 本帖被评价4次，作者chemicalbiology增加金币 2.5 个 | ||
| 当前主题已经存档。 | ||
[资源]
2009年wiley新书非编码RNA章节（总结的很全）
|
||
|
RNA: Noncoding Allison A. Henry and J¨ org Vogel, Max Planck Institute for Infection Biology, Berlin, Germany doi: 10.1002/9780470048672.wecb522 After decades of being either underestimated as a simple messenger in the expression of proteins from deoxyribonucleic acid (DNA), or revered as the molecule from which all life potentially originated, ribonucleic acid (RNA) is at last enjoying a well-deserved golden age as modern techniques allow researchers to uncover the myriad of subtle roles that this molecule plays in the cells of today. Noncoding RNAs, by definition, do not become translated into protein. This broad category includes cellular RNAs that range in size from 20 to 20,000 nucleotides, can contain chemical modifications, adopt a wide variety of secondary and tertiary structures, associate with proteins and other RNA molecules, and have physiological roles, in all organisms, that run the gamut from catalysis to regulating gene expression. As this article is intended to complement the other RNA-related sections of this volume, a brief introduction to all types of noncoding RNA will be followed by a comprehensive discussion of three important categories: riboswitches, small RNAs in bacteria, and large RNAs in mammals. Riboswitches are cis-acting RNA elements that modulate gene expression in a highly specialized manner by means of an aptamer domain, an RNA sequence that tightly and selectively binds a given metabolite. Small RNAs are 70–200 nucleotide molecules in bacteria that regulate gene expression, primarily at a posttranscriptional level. In mammalian cells, large RNAs of up to 19,000 nucleotides are essential to X-chromosome inactivation and genomic imprinting. |
回复此楼» 猜你喜欢
售一区SCI文章T0P，我:8O.551.O54,科目全,可十急
已经有7人回复
-
售SCI一区T0P文章，我:8.O55.1.O.54,科目全,可十急
已经有10人回复
-
售SCI一区T0P文章，我:8O.55.1.O.54,科目全,可伽急
已经有11人回复
-
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有6人回复
-
售SCI一区文章，我:8.O.55.1.O.54,科目齐全,可伽急
已经有13人回复
-
售SCI文章，我:8O5.5.1.O.54,科目齐全,可+急
已经有15人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.54,科目齐全,可+急
已经有10人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有6人回复
-
售SCI一区T0P文章，我:8O.55.1.O.5.4,科目齐全,可+急
已经有7人回复
-
售SCI一区T0P文章，我:8O.55.1.O.54,科目全,可伽急
已经有9人回复
2楼2009-04-17 18:59:17
3楼2009-04-18 10:30:18
4楼2009-04-18 10:36:06
5楼2009-04-18 17:50:10
6楼2009-04-29 15:57:23
简单回复
jacsun7楼
2009-05-10 00:31
回复
好