我们实验室主要研究方向集中在疾病的诊断和治疗方面,具体包括:
(1) Biosensor;
(2) Drug delivery;
(3) Discovery of biomarker of diseases;
(4) Protein/DNA array fabrication.
Professor Wu has the following research focus: (1) Design and fabrication of novel detection systems for disease diagnostics, this includes protein separation systems, protein chips, nanomaterial-based fluorescent/NIR probes, and surface chemistry for protein binding. The goal is to tackle the existing technological challenges in effective detection of low-abundant proteins and post-translational modified proteins in complex biological samples, especially when these proteins are critical in the pathogenesis of chronic diseases. The development of these novel technologies will aid in high-throughput discovery of early biomarkers, non-invasive biomarkers and therapeutic targets for chronic diseases (Lupus, Rheumatoid arthritis, Lupus nephritis, Diabetic nephropathy, Psoriasis, Melanoma etc). In addition, the development of polymer nanofiber based biosensors for biomarker detection has also become of our research interest. (2) Development of versatile and biocompatible nanomaterials for drug delivery to improve bioavailability, effective targeting and controlled release of drugs for chronic diseases. This includes prodrugs and combinatory medicine---the combination of thermotherapy/drug/gene therapy. The goal is to tackle the problems of drug resistance and side-effects commonly seen in today’s medicine for chronic diseases.
欢迎具有生物医学工程,材料科学工程,化学,化工,计算机科学,统计或者编程或相关背景的学生加入我们实验室,我们将围绕疾病的诊断和治疗两方面利用生物化学化工数学计算机等进行相关研究。
休斯顿大学位于全美第四大城市休斯顿市内,发展迅速,休斯顿也是全球最大的医学中心--德克萨斯医学中心所在地。距离休大仅十几分钟车程。对于生物医学工程研究提供很多优越条件。
感兴趣的学生或访问学生, 欢迎联系Prof. Tianfu Wu: twu13@central.uh.edu
主页:http://wulab.bme.uh.edu/ |