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阿尔伯塔大学-牛津大学 糖尿病方向博后招聘
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Dr MacDonald's lab will be hiring into several post-doctoral positions over the next year, including in some newly-funded and exciting projects! Specific details of each position will be posted below. Informal inquiries are welcome. Patrick MacDonald (pmacdonald@ualberta.ca) 1. Postdoctoral Fellow(s) in Islet Biology. Up to two position(s) supported by a CIHR Foundation Grant, and broadly focused on the elucidation of novel pancreatic islet biology in human tissue and/or model systems. Areas of interest include but are not limited to: mechanisms of pancreatic islet cell (dys)function in human health and type 2 diabetes (T2D); collaborative approaches to connect single-cell function with impaired cell identity in T2D and HFD models; metabolic or receptor signaling impacts on the structural determinants of excitability and secretory granule fusion; and novel approaches to phenotyping of islet cells. 2. Postdoctoral Fellow in Mapping of Heterogenous Islet Function (Electrophysiology or Imaging). For this position supported by the NIH as part of the Human Islet Research Network - Human Pancreas Analysis Consortium, we are seeking applicants with experience in electrophysiological or advanced imaging techniques. These approaches will be used to study the excitatory and exocytotic function of human islet cells, either in isolation or within in situ pancreas slice preparations, as part of our efforts to map human islet-cell heterogeneity in situ in collaboration with our international colleagues. 3. Postdoctoral Fellow in Alpha-cell Function in T1D. This position is part of a joint project on functional phenotyping of human alpha-cells in health and T1D and mouse alpha-cells in T1D models; and the application of computational methods/modelling to integrate functional and transcriptomic data-sets. Ideal for someone looking for a mix of cell physiology and computational biology. Note: The position is based in Oxford, UK and is therefore subject to the recruiting policies of the University of Oxford. |
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