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chenyong1302

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专业: 有机化学

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Oxidation of low-density lipoprotein (LDL) has been implicated in atherogenesis. Antioxidants that prevent LDL from oxidizing may reduce atherosclerosis. This study investigated LDL antioxidant activity in edible plant products for development of dietary supplementation to prevent atherosclerosis. Fifty-two kinds of edible plants were extracted using 70% aqueous ethanol solution, and the antioxidant activity of the extracts, which inhibit human LDL oxidation induced by copper ion, was determinedon the basis of the oxidation lag time and represented as epigallocatechin 3-gallate equivalent. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and total phenolic content were also measured for comparisons with antioxidant activityin LDL. Plant products showing the greatest activity in LDL oxidation assay were akamegashiwa (Mallotus japonicus) leaf, Japanese privet (Ligustrum japonicum) leaf, green tea [Camellia sinensis (L.) O. Kuntze], and astringent persimmon (Diospyros kaki). The present study revealed high levels of LDL antioxidant activity in plant products for which such activity levels are underestimated in the DPPH radical scavenging assay and Folin-Ciocalteu assay.
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mayong11

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专业: 药物化学

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chenyong1302(金币+6,VIP+0):谢谢 4-7 16:34

低密度脂蛋白（ LDL ）的氧化包含在动脉硬化中。防止低密度脂蛋白的氧化的抗氧化剂可能会降低动硬化。本研究探讨了在可食用的植物产品中低密度脂蛋白的抗氧化活性，旨在开发膳食补充剂以防止动脉硬化。52种可食用植物中被使用70 ％的乙醇水溶液提取，通过铜离子诱导抑制人低密度脂蛋白氧化，这些萃取物的抗氧化性由是根据氧化延迟时间决定和吗、描述为3 -没食子酸的等价值。测定了DPPH 自由基清除活性和总酚含量，并与低密度脂蛋白氧化活性进行了比较。植物产品展示最大的低密度脂蛋白氧化活性的分别是akamegashiwa 叶，日本女贞（女贞属）叶，绿茶[茶属]和涩柿（亚洲柿子属）。本研究表明，低密度胆固醇偏高的植物产品中抗氧化活性，其DPPH自由基清除能力和福林一Ciocalteu能力被低估了。

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