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US-DOE National Laboratory Postdoctoral Position
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The successful candidate will be a materials scientist or synthetic chemist responsible for designing sequence-defined peptoids for controlled self-assembly into hierarchical structures and/or directing the formation of inorganic (nano)crystals. This researcher will be a team member of a newly-awarded $10.75 million, four-year Energy Frontier Research Center (EFRC) https://www.washington.edu/news/2018/08/03/uw-pnnl-to-host-energy-research-center-focusing-on-bio-inspired-design-and-assembly/. He or She will be frequently interacting with prominent researchers from Pacific Northwest National Laboratory (PNNL) and University of Washington. Instruments that will be used for peptoid synthesis and purification include Aapptec Apex 396 solid-phase synthesizer, Waters SQD2 UPLC-MS system, semi-prep HPLC and lyophilizer. Techniques like atomic force microscope (AFM), TEM, SEM, fluorescence microscope, UV-vis, FT-IR and differential scanning calorimetry (DSC) will be used to characterize peptoid assemblies and/or peptoid-controlled nanoparticle formation. Excellent oral and written communications skills are mandatory. Other duties will include publication of results in peer-reviewed journals, technical presentations at scientific conferences, and development of proposals for new research projects. The candidate must be able to independently design and carry out experiments as well as function productively as part of a multidisciplinary team. Minimum Qualifications Candidates must have received a PhD within the past five years (60 months) or within the next 8 months from an accredited college or university. Preferred Qualifications Ph.D. in chemistry, materials science, polymer science, chemical engineering, or related field Solid background in organic synthesis, supramolecular self-assembly, and soft-matter characterization, Experience using AFM, TEM, SEM, dynamic light scattering, X-ray diffraction, and fluorescent microscope to characterize soft-matter self-assembly and/or bio-controlled crystallization Excellent publication record Demonstrated capability to think and act independently Strong analytical skills Excellent written and oral communication skills Ability to collaborate Contact: Dr. Chun-Long Chen Chunlong.Chen@pnnl.gov Candidates in US will be preferred Selected Publications Related to This Position: 1. Yan, F.; Liu, L.; Walsh, T. R.; Gong, Y.; El-Khoury, P. Z.; Zhang, Y.; Zhu, Z.; De Yoreo J. J.; Engelhard, M. H.; Zhang, X.; Chen, C. L.* Controlled synthesis of highly-branched plasmonic gold nanoparticles through peptoid engineering. Nature Commun. 2018, 9, 2327. DOI: 10.1038/s41467-018-04789-2 (*Corresponding author) https://cleanroomconnect.com/coral-shaped-nanoparticles/ https://www.nanowerk.com/nanotechnology-news/newsid=50431.php https://microscopy-analysis.com/editorials/editorial-listings/bioinspired-materials-breakthrough https://www.cemag.us/news/2018/06/coral-shaped-nanoparticles-built-using-engineered-peptoids https://phys.org/news/2018-06-coral-shaped-nanoparticles-built-peptoids.html 2. Jin, H. B.; Ding, Y.-H.; Wang, M.; Song, Y.; Liao, L.; Newcomb, C. J.; Wu, X.; Tang, X.-Q.; Li, Z.; Lin, Y.; Yan, F.; Jian, T.; Mu, P.; Chen, C. L.* Designable and dynamic single-walled stiff nanotubes assembled from sequenced-defined peptoids. Nature Commun. 2018, 9, 270. DOI: 10.1038/s41467-017-02059-1. (*Corresponding author) https://www.upi.com/Science_News/2018/01/18/New-protein-inspired-nanotube-could-be-used-to-build-water-filtering-membranes/6381516221838/; https://www.eurekalert.org/pub_releases/2018-01/dnnl-ltg011818.php; https://phys.org/news/2018-01-biology-scientists-tiny-tubes-purification.html; https://www.chemicalprocessing.com/industrynews/2018/nanotubes-offer-promise-for-global-water-issues/; https://www.longroom.com/discussion/849435/inspired-by-biology-scientists-created-new-tiny-tubes-that-could-help-with-water-purification-and-tissue-engineering; https://www.sciencenewsline.com/news/2018011817260022.html; https://www.nanowerk.com/nanotechnology-news/newsid=49151.php; https://www.sciencedaily.com/releases/2018/01/180118101447.htm; https://www.tri-cityherald.com/news/local/article206726279.html. 3. Ma, X.; Zhang, S.; Jiao, F.; Newcomb, C. J.; Zhang, Y.; Prakash, A.; Liao, Z.; Baer, M. D.; Mundy, C. J.; Pfaendtner, J.; Noy, A.; Chen, C. L.*; DeYoreo, J. J.*, Tuning crystallization pathways through sequence engineering of biomimetic polymers. Nature Mater. 2017, 16, 767. DOI: 10.1038/NMAT4891. (*Corresponding author) (Journal Cover) 4. Jin, H. B.; Jiao, F.; Daily, M. D.; Chen, Y. L.; Yan, F.; Ding, Y.-H.; Zhang, X.; Robertson, E. J.; Baer, M. D.; Chen, C. L.* Highly stable and self-repairing membrane-mimetic 2D nanomaterials assembled from lipid-like peptoids. Nature Commun. 2016, 7, 12252. DOI: 10.1038/ncomms12252. (*Corresponding author) https://reliawire.com/lipid-like-peptoid-membranes/; https://phys.org/news/2016-07-scientists-thin-material-mimics-cell.html; https://www.sciencedaily.com/releases/2016/07/160719144728.htm; https://www.labonline.com.au/content/lab-equipment/article/a-material-that-mimics-cell-membranes-523732118; https://www.kurzweilai.net/new-nanomaterial-mimics-cell-membranes; https://www.youtube.com/watch?v=qxaFPq0aJVY, https://www.pnnl.gov/news/release.aspx?id=4293. https://www.natureworldnews.com/articles/25521/20160719/scientists-develop-new-thin-material-performs-cell-membranes.htm 本课题组同时欢迎优秀学生以及年青教师来访问交流, 长期有效 Chunlong.Chen@pnnl.gov |
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