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| Participation of the innate system in homeostasis has also been mostly studied in mammalian species.Studies of ¡®¡®knock-out¡¯¡¯ mice lacking different innate machinery like complement components or natural antibodies have demonstrated the vital role of the innate immune system in the maintaining cellular and molecular equilibrium. This applies to both natural processes of cell death (apoptosis) and renewal and maintenance following injury or during acute phase and inflammatory reactions associated with infections. |
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