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北京石油化工学院2026年研究生招生接收调剂公告
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[求助] 年前投稿RSC Advances,审稿意见有一点不知道该如何回答,急求。

年前投稿RSC Advances,审稿意见有一点不知道该如何回答, The authors should be aware of the difficulties of comparing the energies of the mechanisms of two reactions obtained with severe approximations. On the side of the non-enzymatic hydration/dehydration reaction, the employment implicit solvation models (even with the inclusion of 3 explicit water molecules) might be problematic. But it is even worse in the case of the heme-catalyzed reaction: the lack of the rest of the enzyme will probably affect to the results in a great extents. Therefore, although I consider that the results might still be publishable (mainly because it may inspire future works with more reliable methodologies, such as QM/MM simulations or QM dynamics) the authors should acknowledge these possible problems in the discussion. 急求,急求,急求。我打算在结论部分对文章的不足做一些描述,因为我的计算是根据别人做的一个实验来完成的,针对审稿人说的存在的问题,我也不知道该如何回答,不知道该怎么写。求提示。
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