24小时热门版块排行榜    

查看: 2864  |  回复: 181

路小华

木虫 (著名写手)


[交流] 法国FERREIRA Guillaume 教授拟招CSC博士生(神经生物学方向)

法国FERREIRA Guillaume 教授拟招CSC博士生(神经生物学方向)
感兴趣的小伙伴抓紧时间联系,我有师兄在这个机构读博,对FERREIRA Guillaume 教授评价很高,教授人很好,课题组氛围融洽,研究课题十分严谨,如果不是和我专业不太符合,我怎会拱手相让,嘿嘿~~
Department/Institute: Unité Nutrition et Neurobiologie Intégrée
Supervising Scientist: Prof. FERREIRA Guillaume (Directeur de Recherche INRA)
Research Field: Neurobiology
Position: CSC-PhD Student
Project: Role of hippocampal CB1 receptors in obesity-induced memory impairments
Short Description:
In addition to serving as a major risk for cardiovascular and metabolic diseases, obesity is associated with cognitive impairments that pose a substantial threat to quality of life. Our team has been a pioneer in describing memory changes triggered by obesogenic diet consumption in rodent models (Boitard et al., 2012, 2014, 2015, 2016; Tantot et al., 2017; Naneix et al. 2017). In particular, using a combination of genetic and viral approaches, we recently identified that over-activation of the main cannabinoid receptors (CB1R) in hippocampus is a major contributor to obesity-induced memory impairments (Janthakin et al., in preparation). However, we indistinctly manipulated all the CB1R in hippocampus. As CB1R are expressed on different cell types (neurons and astrocytes) and on different cell compartments (plasma and mitochondrial membranes), it remains to identify which CB1R are involved in these effects.
Both neuronal and astroglial CB1R in hippocampus participates in the effects of cannabinoids on memory (Puighermanal et al., Nature Neuroscience, 2009; Han et al., Cell, 2012) and it was recently demonstrated that mitochondrial CB1R in hippocampus mediates memory impairment induced by cannabinoids (Hebert-Chatelain et al., Nature, 2016). Therefore, the main objective of this PhD project will be to identify which cell types (neuronal or astroglial) and which cell compartment (plasma or mitochondrial membranes) in the hippocampus are involved in CB1R-dependent memory impairment in obese mice.
This will improve our understanding of the role played by endocannabinoid system in memory alteration associated with obesity. It will also demonstrate whether manipulation of this system could represent an interesting strategy to alleviate cognitive impairments associated with obesity in order to improve well-being and the quality of life of this growing population.
Requirements:
Please see the attachments.
回复此楼

» 本帖附件资源列表

  • 欢迎监督和反馈:小木虫仅提供交流平台,不对该内容负责。
    本内容由用户自主发布,如果其内容涉及到知识产权问题,其责任在于用户本人,如对版权有异议,请联系邮箱:xiaomuchong@tal.com
  • 附件 1 : UB_CSC_导师和博士专业介绍.pdf
  • 2018-02-04 16:20:36, 588.59 K
  • 附件 2 : UB_CSC2018_申请材料.pdf
  • 2018-02-04 16:20:50, 615.39 K

» 本帖已获得的红花(最新10朵)

» 猜你喜欢

» 本主题相关商家推荐: (我也要在这里推广)

» 抢金币啦!回帖就可以得到:

查看全部散金贴

已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

qdgnq96

金虫 (小有名气)


13楼2018-02-04 17:35:20
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
简单回复
vachelwu2楼
2018-02-04 17:02   回复  
路小华(金币+2): 谢谢参与
2018-02-04 17:24   回复  
路小华(金币+2): 谢谢参与
发自小木虫IOS客户端
syhorchid4楼
2018-02-04 17:25   回复  
路小华(金币+2): 谢谢参与
youngen5楼
2018-02-04 17:27   回复  
路小华(金币+2): 谢谢参与
发自小木虫Android客户端
qdgnq966楼
2018-02-04 17:34   回复  
路小华(金币+2): 谢谢参与
qdgnq967楼
2018-02-04 17:34   回复  
qdgnq968楼
2018-02-04 17:34   回复  
tzynew9楼
2018-02-04 17:34   回复  
路小华(金币+2): 谢谢参与
qdgnq9610楼
2018-02-04 17:34   回复  
qdgnq9611楼
2018-02-04 17:35   回复  
qdgnq9612楼
2018-02-04 17:35   回复  
qdgnq9614楼
2018-02-04 17:35   回复  
qdgnq9615楼
2018-02-04 17:35   回复  
qdgnq9616楼
2018-02-04 17:35   回复  
qdgnq9617楼
2018-02-04 17:35   回复  
qdgnq9618楼
2018-02-04 17:36   回复  
qdgnq9619楼
2018-02-04 17:36   回复  
qdgnq9620楼
2018-02-04 17:36   回复  
time8821楼
2018-02-04 17:39   回复  
路小华(金币+2): 谢谢参与
zuzuksm96622楼
2018-02-04 17:42   回复  
路小华(金币+2): 谢谢参与
zuzuksm96623楼
2018-02-04 17:42   回复  
zuzuksm96624楼
2018-02-04 17:42   回复  
zuzuksm96625楼
2018-02-04 17:42   回复  
zuzuksm96626楼
2018-02-04 17:43   回复  
zuzuksm96627楼
2018-02-04 17:43   回复  
zuzuksm96628楼
2018-02-04 17:43   回复  
zuzuksm96629楼
2018-02-04 17:43   回复  
zuzuksm96630楼
2018-02-04 17:43   回复  
zuzuksm96631楼
2018-02-04 17:43   回复  
zuzuksm96632楼
2018-02-04 17:43   回复  
祝福
zuzuksm96633楼
2018-02-04 17:44   回复  
zuzuksm96634楼
2018-02-04 17:44   回复  
zuzuksm96635楼
2018-02-04 17:44   回复  
zuzuksm96636楼
2018-02-04 17:44   回复  
nono200937楼
2018-02-04 17:46   回复  
路小华(金币+2): 谢谢参与
发自小木虫Android客户端
2018-02-04 17:51   回复  
路小华(金币+2): 谢谢参与
发自小木虫Android客户端
spc0839楼
2018-02-04 17:53   回复  
路小华(金币+2): 谢谢参与
1 发自小木虫IOS客户端
dongmings40楼
2018-02-04 17:54   回复  
路小华(金币+2): 谢谢参与
发自小木虫IOS客户端
2018-02-04 17:55   回复  
路小华(金币+2): 谢谢参与
发自小木虫Android客户端
gengxin6042楼
2018-02-04 17:55   回复  
路小华(金币+2): 谢谢参与
CDkey91843楼
2018-02-04 18:01   回复  
路小华(金币+2): 谢谢参与
祝福祝福 发自小木虫Android客户端
qtejah54744楼
2018-02-04 18:02   回复  
路小华(金币+2): 谢谢参与
2018-02-04 18:02   回复  
路小华(金币+2): 谢谢参与
发自小木虫Android客户端
qtejah54746楼
2018-02-04 18:02   回复  
2018-02-04 18:03   回复  
路小华(金币+2): 谢谢参与
up 发自小木虫IOS客户端
2018-02-04 18:08   回复  
路小华(金币+2): 谢谢参与
发自小木虫Android客户端
稚硕mc149楼
2018-02-04 18:15   回复  
路小华(金币+2): 谢谢参与
欢欢7750楼
2018-02-04 18:16   回复  
路小华(金币+2): 谢谢参与
发自小木虫Android客户端
相关版块跳转 我要订阅楼主 路小华 的主题更新
普通表情 高级回复 (可上传附件)
信息提示
请填处理意见