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[求助] 求大神帮忙指导怎么回答大致是什么意思?急!

急求大神帮忙分析怎么回答审稿人的意见,意见如下:
1.Calibration curve was established in matrix, how many independent replicates for each level? Injected in duplicate? Was the matrix effect evaluated? How? Was the standard calibration significantly different from matrix calibration? Which statistical test was used to compare? Please indicate the slope and intercept standard deviation. Please explain how precision was determined (see ICH guidelines).
2. According to the obtained values in the case of real sample, was necessary the application of correction factor? How was decided?
3. According to the obtained values in the case of real sample, was necessary the application of correction factor? How was decided?
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