±±¾©Ê¯ÓÍ»¯¹¤Ñ§Ôº2026ÄêÑо¿ÉúÕÐÉú½ÓÊÕµ÷¼Á¹«¸æ
²é¿´: 1547  |  »Ø¸´: 9
¡¾½±Àø¡¿ ±¾Ìû±»ÆÀ¼Û8´Î£¬×÷ÕßyalefieldÔö¼Ó½ð±Ò 8 ¸ö
µ±Ç°Ö÷ÌâÒѾ­´æµµ¡£

yalefield

½ð³æ (ÎÄ̳¾«Ó¢)


[×ÊÔ´] ÐÂÊ飺Pharmacokinetic-Pharmacodynamic Modeling and Simulation

Pharmacokinetic-Pharmacodynamic Modeling and Simulation
Publisher: Springer | 2005-10-20 | 387 pages | ISBN: 038727197X | 7.6 MB |

A natural hierarchy exists in pharmacokinetic-pharmacodynamic modeling culminating in population pharmacokinetic models, which are a specific type of nonlinear mixed effects model. The purpose of this book is to present through theory and example how to develop pharmacokinetic models, both at an individual and population level. In order to do so, however, one must first understand linear models and then build to nonlinear models followed by linear mixed effects models and then ultimately nonlinear mixed effects models. This book develops in that manner each chapter builds upon previous chapters by first presenting the theory and then illustrating the theory using published data sets and actual data sets that were used in the development of new chemical entities collected by the author during his years in industry. A key feature of the book is the process of modeling. Most books and manuscripts often present the final model never showing how the model evolved. In this book all examples are presented in an evolutionary manner.

°³ÕýÔÚÏÂÔØ......
http://www.ebookee.com.cn/Pharma ... ulation_159367.html
http://www.ebookee.com.cn/Pharmacokinetic-Pharmacodynamic-Modeling-and-Simulation_159367.html
»Ø¸´´ËÂ¥

» ²ÂÄãϲ»¶

ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

ÅÝÅÝ-211

ÖÁ×ðľ³æ (ÖªÃû×÷¼Ò)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

Â¥Ö÷£¬ÔõôÏÂÔØ°¡£¿
2Â¥2009-01-19 08:01:41
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

huaxingjin

ľ³æ (ÖøÃûдÊÖ)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

ÎÒÏÂÔØÁË£¬Ð»Ð»À²£¡
3Â¥2009-01-19 23:22:39
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

lassa

½ð³æ (СÓÐÃûÆø)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

º¹¡£¡£¡£¡£¡£»¹ÊǰïÀϺºÌù¸öµØÖ·°É
Ò»¸ÉÈ˵ȶ¼²»×¢Òâ¿´ÄÚÈÝ¡£¡£¡£¡£

http://rapidshare.com/files/9500 ... _and_Simulation.rar
6Â¥2009-01-23 16:39:45
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

hnldf

ľ³æ (ÕýʽдÊÖ)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

·Ç³£ºÃ£¬¿ÉÊÇÎÒÕÒ²»µ½¡£
7Â¥2009-10-18 20:29:35
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

hnldf

ľ³æ (ÕýʽдÊÖ)


ϲ»ÁË£¡
8Â¥2009-10-22 08:18:18
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

newztl

ľ³æ (ÕýʽдÊÖ)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

Ç¿ÁÒÍÆ¼ö
9Â¥2009-10-28 15:36:52
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

huqiu1953

ľ³æ (ÎÄ̳¾«Ó¢)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

Â¥Ö÷£¬ÎªÊ²Ã´ÎÒϲ»ÁËÄØ£¿¼±¡£¡£¡£
Èç¹û·½±ãµÄ»°£¬ÄÜ·¢·Ýµ½ÎÒµÄÓÊÏäÂð£¿huqiu1953@163.com
10Â¥2010-01-13 14:51:31
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
¼òµ¥»Ø¸´
2009-01-20 19:59   »Ø¸´  
 
daoke20055Â¥
2009-01-21 15:59   »Ø¸´  
 
Ïà¹Ø°æ¿éÌø×ª ÎÒÒª¶©ÔÄÂ¥Ö÷ yalefield µÄÖ÷Ìâ¸üÐÂ
¡î ÎÞÐǼ¶ ¡ï Ò»ÐǼ¶ ¡ï¡ï¡ï ÈýÐǼ¶ ¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] 311£¨085601£©Çóµ÷¼Á +4 liziyeyeye 2026-03-28 4/200 2026-03-28 18:50 by 535743368
[¿¼ÑÐ] 394Çóµ÷¼Á +3 ºÃʶàÄ¥¾²ºò¼ÑÒ 2026-03-26 5/250 2026-03-28 14:24 by ÌÆãå¶ù
[¿¼ÑÐ] ¡¾Çóµ÷¼Á¡¿085601²ÄÁϹ¤³Ìר˶ | ×Ü·Ö272 | +6 ½Å»¬µÄÊØ·¨¹«Ãñ 2026-03-27 6/300 2026-03-28 11:02 by gjlllb
[¿¼ÑÐ] 085405 ¿¼µÄ11408Çó¸÷λÀÏʦ´ø×ß +3 Qiuѧing 2026-03-28 3/150 2026-03-28 09:19 by ÀֺǺǵÄ×·ÃÎÈË
[¿¼ÑÐ] ²ÄÁÏÇóµ÷¼Á Ò»Ö¾Ô¸¹þ¹¤´ó×Ü·Ö298·Ö£¬Ç°Èý¿Æ223·Ö +5 dongfang59 2026-03-27 5/250 2026-03-28 04:53 by wxiongid
[¿¼ÑÐ] »¯Ñ§µ÷¼Á +4 °®³Ô·¬ÇѵÄÐñ 2026-03-24 5/250 2026-03-27 17:50 by kiokin
[¿¼ÑÐ] ¿¼Ñе÷¼Á +4 Sanmu-124 2026-03-26 4/200 2026-03-27 17:49 by kiokin
[¿¼ÑÐ] ²ÄÁÏÓ뻯¹¤085600£¬×Ü·Ö304£¬±¾¿ÆÓÐÁ½Æªsci²ÎÓ룬Çóµ÷¼Á +10 ÐÒÔ˵Ľ´½´ 2026-03-22 12/600 2026-03-27 16:08 by muchong357
[¿¼ÑÐ] 287Çóµ÷¼Á +10 land xuxu 2026-03-26 10/500 2026-03-27 15:33 by ÅÁ¶ûÂíÀ­ÌØ
[¿¼ÑÐ] ²ÄÁÏÇóµ÷¼Á +5 .m.. 2026-03-25 5/250 2026-03-27 11:08 by ²»³Ôô~µÄ؈
[¿¼ÑÐ] Çóµ÷¼Á£¬Ò»Ö¾Ô¸ ÄϾ©º½¿Õº½Ìì´óѧ´óѧ £¬080500²ÄÁÏ¿ÆÑ§Ó빤³Ìѧ˶ +4 @taotao 2026-03-26 5/250 2026-03-27 08:10 by hypershenger
[¿¼ÑÐ] 329Çóµ÷¼Á +7 Å¥¶÷Ñ© 2026-03-25 7/350 2026-03-27 04:28 by wxiongid
[¿¼ÑÐ] 085602 289·ÖÇóµ÷¼Á +8 WWWÎ÷Î÷¸¥Ë¹ 2026-03-24 8/400 2026-03-26 16:33 by ²»³Ôô~µÄ؈
[¿¼ÑÐ] 081700 µ÷¼Á 267·Ö +11 ÃÔÈ˵Ĺþ¹þ 2026-03-23 11/550 2026-03-26 15:41 by zzll406
[¿¼ÑÐ] »·¾³×¨Ë¶324·ÖÇóµ÷¼ÁÍÆ¼ö +5 ÐùСÄþ¡ª¡ª 2026-03-26 5/250 2026-03-26 12:05 by i_cooler
[¿¼ÑÐ] 332Çóµ÷¼Á +6 032500 2026-03-25 6/300 2026-03-25 22:45 by 418490947
[¿¼ÑÐ] 290·Öµ÷¼ÁÇóÖú +3 ¼ªÏéÖ¹Ö¹³Â 2026-03-25 3/150 2026-03-25 19:58 by barlinike
[¿¼ÑÐ] ²ÄÁÏר˶ 335 ·ÖÇóµ÷¼Á +4 ¾Ü¾øÀ䱩Á¦ 2026-03-25 4/200 2026-03-25 18:45 by haxia
[¿¼ÑÐ] 347Çóµ÷¼Á +4 L when 2026-03-25 4/200 2026-03-25 13:37 by cocolv
[¿¼ÑÐ] Ò»Ö¾Ô¸¼ª´ó»¯Ñ§322Çóµ÷¼Á +4 17501029541 2026-03-23 6/300 2026-03-24 10:21 by ´÷Χ²±µÄСÎÃ×Ó
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û