| ²é¿´: 765 | »Ø¸´: 7 | ||||
523156717½ð³æ (ÖøÃûдÊÖ)
|
[ÇóÖú]
°ïæ²éÊDz»ÊÇsci¼ìË÷ ÒÑÓÐ2È˲ÎÓë
|
|
Relative tissue distribution and excretion studies of gastrodin and parishin from power and extract of Gastrodiae Rhizoma in rat bx UHPLC-ESI-MS/MS Zhengmeng Jiang Guizhou Normal University ·¢×ÔСľ³æIOS¿Í»§¶Ë |
» ²ÂÄãϲ»¶
²ÄÁϵ÷¼Á
ÒѾÓÐ4È˻ظ´
304Çóµ÷¼Á
ÒѾÓÐ14È˻ظ´
Çóµ÷¼Á
ÒѾÓÐ24È˻ظ´
Ò»Ö¾Ô¸»ª¶«Àí¹¤085601²ÄÁϹ¤³Ì303·ÖÇóµ÷¼Á
ÒѾÓÐ7È˻ظ´
288»·¾³×¨Ë¶,Çóµ÷²ÄÁÏ·½Ïò
ÒѾÓÐ25È˻ظ´
0703»¯Ñ§
ÒѾÓÐ25È˻ظ´
Çóµ÷¼Á Ò»Ö¾Ô¸Î÷ÄϽ»Í¨´óѧ085701»·¾³¹¤³Ì 282·Ö
ÒѾÓÐ12È˻ظ´
Ò»Ö¾Ô¸211£¬»¯Ñ§Ñ§Ë¶£¬310·Ö£¬±¾¿ÆÖصãË«·Ç£¬Çóµ÷¼Á
ÒѾÓÐ3È˻ظ´
Ò»Ö¾Ô¸211£¬0703»¯Ñ§305·ÖÇóµ÷¼Á
ÒѾÓÐ12È˻ظ´
Ò»Ö¾Ô¸211£¬»¯Ñ§Ñ§Ë¶£¬310·Ö£¬±¾¿ÆÖصãË«·Ç£¬Çóµ÷¼Á
ÒѾÓÐ4È˻ظ´
» ±¾Ö÷ÌâÏà¹Ø¼ÛÖµÌùÍÆ¼ö£¬¶ÔÄúͬÑùÓаïÖú:
ѯÎÊÆÚ¿¯ Advances in Science and Technology ÊDz»ÊÇSCI ?
ÒѾÓÐ3È˻ظ´
Çë°ïæ²éÒ»ÏÂÕâÆªÎÄÕÂÊDz»ÊDZ»SCI¼ìË÷ÁË£¬Ð»Ð»
ÒѾÓÐ2È˻ظ´
ÎÄÕÂÊÇ·ñ±»SCI¼ìË÷
ÒѾÓÐ6È˻ظ´
ÄÄλºÃÐÄÈ˰ïæ²éһƪÎÄÕµÄSCI¼ìË÷ºÅ£¬»Ò³£»Ò³£¸Ðл°¡
ÒѾÓÐ1È˻ظ´
ÖÕÓÚÍê³ÉÁ˵ÚһƪÂÛÎÄ¡¡µÄ³õ¸å
ÒѾÓÐ26È˻ظ´
Ôõô¼ìË÷SCIÎÄÏ×
ÒѾÓÐ9È˻ظ´
ÒÔϼ¸¸ö»áÒéÊÇ·ñ±»ISTP¼ìË÷
ÒѾÓÐ2È˻ظ´
¸Ã²»¸Ã¶ÁÐźÅÓëÐÅÏ¢´¦ÀíµÄ²©Ê¿
ÒѾÓÐ19È˻ظ´
¸Ã²»¸Ã¿¼ÐźÅÓëÐÅÏ¢´¦ÀíµÄ²©Ê¿
ÒѾÓÐ3È˻ظ´
¸Ã²»¸Ã¿¼ÐźÅÓëÐÅÏ¢´¦ÀíµÄ²©Ê¿
ÒѾÓÐ1È˻ظ´
ÇóÖú¹ØÓÚSCIºÍEIµÄÏà¹ØÄÚÈÝ
ÒѾÓÐ1È˻ظ´
Çë´ó¼Ò°ïæ²éÒ»ÏÂÕâÁ½ÆªÎÄÕÂÊÇ·ñ±»SCIÊÕ¼
ÒѾÓÐ1È˻ظ´
ÇëÎÊNatural Science Õâ¸öÔÓÖ¾
ÒѾÓÐ1È˻ظ´
SCIºÍEIË÷ÒýºÅ²éѯ
ÒѾÓÐ1È˻ظ´
523156717
½ð³æ (ÖøÃûдÊÖ)
- Ó¦Öú: 16 (СѧÉú)
- ½ð±Ò: 2393.8
- É¢½ð: 2764
- ºì»¨: 14
- Ìû×Ó: 1209
- ÔÚÏß: 410.1Сʱ
- ³æºÅ: 2769835
- ×¢²á: 2013-11-01
- ÐÔ±ð: GG
- רҵ: »·¾³ÎÛȾ»¯Ñ§
2Â¥2017-06-08 12:48:49
523156717
½ð³æ (ÖøÃûдÊÖ)
- Ó¦Öú: 16 (СѧÉú)
- ½ð±Ò: 2393.8
- É¢½ð: 2764
- ºì»¨: 14
- Ìû×Ó: 1209
- ÔÚÏß: 410.1Сʱ
- ³æºÅ: 2769835
- ×¢²á: 2013-11-01
- ÐÔ±ð: GG
- רҵ: »·¾³ÎÛȾ»¯Ñ§
3Â¥2017-06-08 12:54:26
tepa2008
½ð³æ (ÖªÃû×÷¼Ò)
- Ó¦Öú: 32 (СѧÉú)
- ½ð±Ò: 7152.6
- É¢½ð: 12670
- ºì»¨: 10
- Ìû×Ó: 8685
- ÔÚÏß: 696.2Сʱ
- ³æºÅ: 598417
- ×¢²á: 2008-09-10
¡¾´ð°¸¡¿Ó¦Öú»ØÌû
¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï
¸Ðл²ÎÓ룬ӦÖúÖ¸Êý +1
523156717: ½ð±Ò+20 2017-06-09 13:29:01
¸Ðл²ÎÓ룬ӦÖúÖ¸Êý +1
523156717: ½ð±Ò+20 2017-06-09 13:29:01
|
Relative tissue distribution and excretion studies of gastrodin and parishin from powder and extract of Gastrodiae Rhizoma in rat by UHPLC-ESI-MS/MS. ×÷Õß:Jiang, Zhengmeng; Zheng, Xiuyan; Gong, Xiaojian; Zhao, Chao; Zhou, Xin; Zhao, Yang; Yan, Yanfang Biomedical chromatography : BMC DOI:10.1002/bmc.3909 ³ö°æÄê:2016-Dec-07 (Epub 2016 Dec 07) ÕªÒª New research has indicated that Gastrodiae Rhizome (GR) has potential anti-diabetic and anti-asthmatic effects in mouse models. On the basis of our previous study of the relative bioavailability of gastrodin (GAS) and parishin (PA) from extract and powder of GR, we performed further research on the tissue distribution and excretion of the two analytes. A reliable bioanalytical method for the quantification of GAS and PA in rat tissues and excretion is required. Chromatographic separation was carried out on a gradient mobile phase of acetonitrile-water with 0.1% formic acid. Calibration curves (1/x2 weighted) offered satisfactory linearity (r2 >0.9835) within 100-3000ngmL-1 for GAS and (r2 >0.9862) within 10-1000ngmL-1 for PA. The relative standard deviations of the intra-day and inter-day precision were all <14.98%, whilst the relative errors of the intra-day and inter-day accuracy were all within ¡À14.71%. The matrix effect and recovery values were satisfactory in all of the biological matrices examination. The data of relative differences in tissue distribution and excretion of GAS and PA from powder and extract of GR indicated that higher bioavailabilities for GAS and PA were obtained when a dosage of 4gkg-1 GR powder was used. Copyright 2016 John Wiley & Sons, Ltd. ¹Ø¼ü´Ê ¹Ø¼ü´ÊÁбí:Gastrodiae Rhizome; UHPLC-ESI-MS/MS; bioavailability; gastrodin and parishin; tissue distribution and excretion studies ×÷ÕßÐÅÏ¢ µØÖ·:Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, People's Republic of China. ÎÄÏ×ÐÅÏ¢ ÎÄÏ×ÀàÐÍ:Journal Article ÓïÖÖ:English PubMed ID:27925254 NLM Ψһ ID:8610241 ´´½¨ÈÕÆÚ: 07 Dec 2016 ÐÞ¶©ÈÕÆÚ: 24 Jan 2017 µç×Ó³ö°æ:07 Dec 2016 ¹ú¼Ò/µØÇø: England ISSN:1099-0801 ºÃÏñ²»ÊÇSCI |
4Â¥2017-06-08 13:12:13
tepa2008
½ð³æ (ÖªÃû×÷¼Ò)
- Ó¦Öú: 32 (СѧÉú)
- ½ð±Ò: 7152.6
- É¢½ð: 12670
- ºì»¨: 10
- Ìû×Ó: 8685
- ÔÚÏß: 696.2Сʱ
- ³æºÅ: 598417
- ×¢²á: 2008-09-10
5Â¥2017-06-08 13:13:51
523156717
½ð³æ (ÖøÃûдÊÖ)
- Ó¦Öú: 16 (СѧÉú)
- ½ð±Ò: 2393.8
- É¢½ð: 2764
- ºì»¨: 14
- Ìû×Ó: 1209
- ÔÚÏß: 410.1Сʱ
- ³æºÅ: 2769835
- ×¢²á: 2013-11-01
- ÐÔ±ð: GG
- רҵ: »·¾³ÎÛȾ»¯Ñ§
6Â¥2017-06-08 13:15:15
tepa2008
½ð³æ (ÖªÃû×÷¼Ò)
- Ó¦Öú: 32 (СѧÉú)
- ½ð±Ò: 7152.6
- É¢½ð: 12670
- ºì»¨: 10
- Ìû×Ó: 8685
- ÔÚÏß: 696.2Сʱ
- ³æºÅ: 598417
- ×¢²á: 2008-09-10
7Â¥2017-06-08 13:28:22
paperhunter
ÈÙÓþ°æÖ÷ (ÎÄѧ̩¶·)
»¹Ã»ÏëºÃ
-

ר¼Ò¾Ñé: +14 - SEPI: 1
- Ó¦Öú: 14603 (½ÌÊÚ)
- ¹ó±ö: 11.659
- ½ð±Ò: 345467
- É¢½ð: 9262
- ºì»¨: 1423
- ɳ·¢: 2016
- Ìû×Ó: 127554
- ÔÚÏß: 8880.4Сʱ
- ³æºÅ: 971012
- ×¢²á: 2010-03-14
- רҵ: »·¾³¹¤³Ì
- ¹ÜϽ: ÂÛÎÄͶ¸å
¡¾´ð°¸¡¿Ó¦Öú»ØÌû
¸Ðл²ÎÓ룬ӦÖúÖ¸Êý +1
|
BIOMEDICAL CHROMATOGRAPHY Monthly ISSN: 0269-3879 WILEY, 111 RIVER ST, HOBOKEN, USA, NJ, 07030-5774 Coverage Science Citation Index Science Citation Index Expanded Current Contents - Life Sciences BIOSIS Previews SCI¼ìË÷µÄÆÚ¿¯ÉÏ·¢±íµÄÎÄÕ»ᱻSCI¼ìË÷£¬²»¹ýʱ¼ä²»Í¬£¬ÓÐЩÆÚ¿¯¿ÉÄÜÐèÒª°ëÄê×óÓÒ¡£ |

8Â¥2017-06-08 23:13:49














»Ø¸´´ËÂ¥