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¡¶Canadian Journal of Gastroenterology and Hepatology¡·(Ó°ÏìÒò×Ó2.307)Õ÷¸åÆôʾ ÒÑÓÐ3È˲ÎÓë
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¡¶Canadian Journal of Gastroenterology and Hepatology¡·Õ÷¸åÆôÊ ´ËÆÚ¿¯ÏÖÓÐרÀ¸Õ÷¸å£¬¡°Immunometabolic Disorders and Liver Diseases¡±£¬»¶Ó¸÷λ¸ÐÐËȤµÄÀÏʦ£¬Í¬Ñ§Í¶¸å¡£Á´½Ó£ºhttps://www.hindawi.com/journals/cjgh/si/518262/cfp/ Immunometabolic Disorders and Liver Diseases Call for Papers The prevalence of metabolic liver diseases (MLD) is increasing dramatically in both developing and industrialized countries, causing a big burden to society. MLD is largely attributed to unhealthy lifestyle choices, including caloric-over-consumption, lack of exercise, and circadian rhythm disruption. Notably, unresolved metabolic disorders, accompanied by chronic inflammation, will cause liver damage and fibrosis and eventually promote hepatocellular carcinoma. Therefore, elucidation of mechanisms underlying MLD progression together with development of efficient therapeutic strategies against it is essential and urgent. In recent years, a noticeable number of findings have unveiled the modulation of metabolic homeostasis by the immune system. In the setting of MLD, metabolic stress (e.g., liver steatosis, hypoxia) predisposes liver cells to injury caused by dysregulated inflammatory responses and aberrant cytokine production, which in turn exacerbates metabolic comorbidities. Accordingly, intrahepatic immune cells as well as hepatic inflammatory pathways are promising targets for strategies against MLD. This special issue is to promote the researches that investigate the interplay between inflammatory/immune pathways and metabolic liver diseases, which will provide novel insights into this emerging field. Research articles and reviews relating to liver metabolism, inflammation, and immunity are especially encouraged to be submitted to this special issue. Potential topics include but are not limited to the following: Hepatic glucose/lipid disorders and immune response Alcoholic liver disease and immune responses Nonalcoholic fatty liver disease (NAFLD) and immune responses MLD and liver inflammation MLD and liver injury/fibrosis Epidemiological studies of MLD and immune system Clinical studies involved in MLD and immune responses Pharmaceutical investigation of MLD treatment Authors can submit their manuscripts through the Manuscript Tracking System at https://mts.hindawi.com/submit/journals/cjgh/hepatology/mld/. Submission Deadline Friday, 27 October 2017 Publication Date March 2018 Papers are published upon acceptance, regardless of the Special Issue publication date. Lead Guest Editor Hong Shen, University of Michigan, Ann Arbor, USA Guest Editors Mark J. Canet, University of Michigan, Ann Arbor, USA Liang Sheng, Nanjing Medical University, Nanjing, China Feihua Wu, China Pharmaceutical University, Nanjing, China Kae W. Cho, Soonchunhyang University, Asan, Republic of Korea Qilin Gu, Houston Methodist Research Institute, Houston, USA |
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