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武大木虫 (著名写手)
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Science：澳研究发现共生菌可让蚊子寿命减半
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澳大利亚科学家1月2日公布一项报告显示，沃尔巴克氏共生菌能让蚊子寿命减半，从而可较为简单经济地减少借蚊虫传播的疟疾、登革热等传染病。 沃尔巴克氏体广泛存在于果蝇等节肢动物体内，经宿主母系细胞质遗传。由于它通常能让果蝇寿命减半，研究人员让埃及伊蚊感染上沃尔巴克氏体，置于严格受控的实验室中孵化后代。 结果显示，出生时携带沃尔巴克氏体的埃及伊蚊即使在环境舒适的实验室内也只能存活21天，正常蚊子则能生存50天。 Science 2 January 2009: Vol. 323. no. 5910, pp. 141 - 144 DOI: 10.1126/science.1165326 Stable Introduction of a Life-Shortening Wolbachia Infection into the Mosquito Aedes aegypti Conor J. McMeniman, 1 Roxanna V. Lane, 1 Bodil N. Cass, 1 Amy W.C. Fong, 1 Manpreet Sidhu, 1 Yu-Feng Wang, 1 ,2 Scott L. O'Neill 1 Most pathogens require a relatively long period of development in their mosquito vector before they can be transmitted to a new human host; hence, only older insects are of epidemiological importance. The successful transfer of a life-shortening strain of the inherited bacterial symbiont, Wolbachia , into the major mosquito vector of dengue, Aedes aegypti , halved adult life span under laboratory conditions. The association is stable, and the Wolbachia strain is maternally inherited at high frequency. It is capable of inducing complete cytoplasmic incompatibility, which should facilitate its invasion into natural field populations and its persistence over time. Our data suggest that targeting mosquito age with inherited Wolbachia infections may be a viable strategy to reduce the transmission of pathogens such as dengue viruses. 1 School of Integrative Biology, The University of Queensland, Brisbane 4072, Australia. 2 College of Life Sciences, Central China Normal University, Wuhan 430079, China. |
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