http://www.ivdshow.cn
表观遗传学(m6A RNA甲基化、RNA甲基化、DNA甲基化、DNA羟甲基、DNA甲酰基、DNA羧基),分子生物学,免疫生物学(一抗、二抗),细胞生物学,实验仪器学(核酸提起仪、超微量分光光度计)等等产品与技术服务
北京市昌平区中关村生命科学园东60米艾德园
联系人: Peter Chen / 邮箱: 1951545998@qq.com / QQ: 1513545070 / 电话: 0313-5935521 / 手机: 18911529660
查看: 1310  |  回复: 107
当前只显示满足指定条件的回帖,点击这里查看本话题的所有回帖

ADTechnology

捐助贵宾 (著名写手)

表观遗传学专业供应商

[商家供应] Magna m6A RNA甲基化免疫沉淀试剂盒-特定位点检测

本商家没有参加优惠活动,一起邀请他来参加吧 我的代金券

代金券0元
限量 x 张
满 x 可使用;有效期 x 天;过期可退

内容

针对特定位点的 m6A RNA甲基化,全球顶级检测方法。具体参考如下:
Magna m6A RNA甲基化免疫沉淀试剂盒-特定位点检测                                             货号:A-17-10499

Magna MeRIP™ m6A Kit- Transcriptome-wide Profiling of N6-Methyladenosine

背景资料:N6-methyladenosine (m6A) represents an abundant RNA modification that is conserved across many different species, ranging from plants, to yeast, to mammals. Similar to the 5-methylcytosine (5-mc) modification of DNA, m6A is a reversible chemical modification of RNA. m6A RNA modifications are an emerging topic in controlling cell fate transitions in mammalian embryonic stem cells. m6A is one of the most prevalent modifications on both mRNAs and noncoding RNAs in eukaryotes with an estimated 12,000 m6A sites in over 7,000 genes. The mark is deposited by a heterodimer of methyltransferase-like 3 and 14 (Mettl3 and Mettl14) and can be removed by the RNA demethylase enzymes FTO and ALKBH5. Obesity risk gene FTO encodes the first identified m6A demethylase. Mutations in FTO have been associated with increased risk for obesity and type II diabetes. Recently, impairment of the status of m6A regulation has lead to prolonged expression of Nanog in ES cells and the inability to exit self-renewal stages toward differentiation。

产品描述:Methylated (m6A) RNA immunoprecipitation (MeRIP) is a method to monitor the status of m6A and map the location of m6A RNA modifications transcriptome-wide. The Magna MeRIP M6A Kit uses the MeRIP method to enable identification and transcriptome-wide profiling of m6A RNA modifications. In the MeRIP assay, RNA is chemically fragmented into 100 nucleotides or smaller fragments followed by magnetic immunoprecipitation with a monoclonal antibody toward m6A. After immunoprecipitation, isolated RNA fragments can be subjected with qRT-PCR or RNA sequencing (MeRIP-seq). The streamlined protocol is easy to process and can produce results with high SN ratios。

产品特点:

1·Complete collection of MeRIP valiidated reagents to streamline the MeRIP method;

2·High signal to noise ratios using high affinity m6A monoclonal antibody and A/G magnetic beads ;

3.Stem cell validated;

4.The Magna MeRIP M6A Kit provides sufficient reagents for 10 MeRIP reactions using 5 μg of mRNA or 5 MeRIP reactions when 300 μg of total RNA is used;

5.Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals。

保存建议:在接收到艾德寄出的试剂盒后请按照说明书建议,使用不同的保存条件或温度来保存试剂盒内组分。
相关的资料,请下载参考附件。

» 本帖附件资源列表

» 猜你喜欢

» 抢金币啦!回帖就可以得到:

查看全部散金贴

已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

沙上鱼

禁虫 (文坛精英)


ADTechnology(金币+1): 谢谢参与
本帖内容被屏蔽

97楼2017-02-09 17:44:48
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
查看全部 108 个回答

ADTechnology

捐助贵宾 (著名写手)

表观遗传学专业供应商

好产品。
表观遗传学(m6A RNA甲基化、RNA甲基化、DNA甲基化、DNA羟甲基、DNA甲酰基、DNA羧基),分子生物学,免疫生物学(一抗、二抗),细胞生物学,实验仪器学(核酸提起仪、超微量分光光度计)等等产品与技术服务
北京市昌平区中关村生命科学园东60米艾德园
联系人: Peter Chen / 邮箱: 1951545998@qq.com / QQ: 1513545070 / 电话: 0313-5935521 / 手机: 18911529660
3楼2017-02-09 09:29:48
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
11楼2017-02-09 10:00:19
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
14楼2017-02-09 10:03:51
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
普通表情 高级回复 (可上传附件)
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[考研] 288求调剂,一志愿华南理工大学071005 +5 ioodiiij 2026-03-17 5/250 2026-03-19 18:22 by zcl123
[考研] 【考研调剂】化学专业 281分,一志愿四川大学,诚心求调剂 +5 吃吃吃才有意义 2026-03-19 5/250 2026-03-19 16:18 by 30660438
[考研] 本人考085602 化学工程 专硕 +17 不知道叫什么! 2026-03-15 19/950 2026-03-19 15:06 by 尽舜尧1
[考研] 0703化学调剂 +5 pupcoco 2026-03-17 8/400 2026-03-19 13:58 by houyaoxu
[考研] 295求调剂 +3 一志愿京区211 2026-03-18 5/250 2026-03-18 17:03 by zhaoqian0518
[考研] 材料专硕306英一数二 +10 z1z2z3879 2026-03-16 13/650 2026-03-18 14:20 by 007_lilei
[考研] 302求调剂 +10 呼呼呼。。。。 2026-03-17 10/500 2026-03-18 12:45 by Linda Hu
[考研] 299求调剂 +5 △小透明* 2026-03-17 5/250 2026-03-18 11:49 by 尽舜尧1
[考研] 工科材料085601 279求调剂 +6 困于星晨 2026-03-17 6/300 2026-03-18 10:21 by kkcoco25
[考研] 考研求调剂 +3 橘颂. 2026-03-17 4/200 2026-03-17 21:43 by 有只狸奴
[考研] 277调剂 +5 自由煎饼果子 2026-03-16 6/300 2026-03-17 19:26 by 李leezz
[考研] 材料专硕326求调剂 +6 墨煜姒莘 2026-03-15 7/350 2026-03-17 17:10 by ruiyingmiao
[考研] 11408 一志愿西电,277分求调剂 +3 zhouzhen654 2026-03-16 3/150 2026-03-17 07:03 by laoshidan
[考研] 东南大学364求调剂 +5 JasonYuiui 2026-03-15 5/250 2026-03-16 21:28 by 木瓜膏
[考研] 0703一志愿211 285分求调剂 +5 ly3471z 2026-03-13 5/250 2026-03-16 16:16 by 哦哦123
[考研] 070300化学学硕求调剂 +6 太想进步了0608 2026-03-16 6/300 2026-03-16 16:13 by kykm678
[考研] 288求调剂 +4 奇点0314 2026-03-14 4/200 2026-03-14 23:04 by JourneyLucky
[考研] 学硕285求调剂 +13 Wisjxn 2026-03-12 46/2300 2026-03-14 10:33 by JourneyLucky
[硕博家园] 085600 260分求调剂 +3 天空还下雨么 2026-03-13 5/250 2026-03-13 18:46 by 天空还下雨么
[考研] 333求调剂 +3 152697 2026-03-12 4/200 2026-03-13 07:08 by Iveryant
信息提示
请填处理意见