| 查看: 1270 | 回复: 107 | ||
| 当前只显示满足指定条件的回帖,点击这里查看本话题的所有回帖 | ||
ADTechnology
|
[商家供应]
Magna m6A RNA甲基化免疫沉淀试剂盒-特定位点检测
|
|
针对特定位点的 m6A RNA甲基化,全球顶级检测方法。具体参考如下:Magna m6A RNA甲基化免疫沉淀试剂盒-特定位点检测 货号:A-17-10499 Magna MeRIP™ m6A Kit- Transcriptome-wide Profiling of N6-Methyladenosine 背景资料:N6-methyladenosine (m6A) represents an abundant RNA modification that is conserved across many different species, ranging from plants, to yeast, to mammals. Similar to the 5-methylcytosine (5-mc) modification of DNA, m6A is a reversible chemical modification of RNA. m6A RNA modifications are an emerging topic in controlling cell fate transitions in mammalian embryonic stem cells. m6A is one of the most prevalent modifications on both mRNAs and noncoding RNAs in eukaryotes with an estimated 12,000 m6A sites in over 7,000 genes. The mark is deposited by a heterodimer of methyltransferase-like 3 and 14 (Mettl3 and Mettl14) and can be removed by the RNA demethylase enzymes FTO and ALKBH5. Obesity risk gene FTO encodes the first identified m6A demethylase. Mutations in FTO have been associated with increased risk for obesity and type II diabetes. Recently, impairment of the status of m6A regulation has lead to prolonged expression of Nanog in ES cells and the inability to exit self-renewal stages toward differentiation。 产品描述:Methylated (m6A) RNA immunoprecipitation (MeRIP) is a method to monitor the status of m6A and map the location of m6A RNA modifications transcriptome-wide. The Magna MeRIP M6A Kit uses the MeRIP method to enable identification and transcriptome-wide profiling of m6A RNA modifications. In the MeRIP assay, RNA is chemically fragmented into 100 nucleotides or smaller fragments followed by magnetic immunoprecipitation with a monoclonal antibody toward m6A. After immunoprecipitation, isolated RNA fragments can be subjected with qRT-PCR or RNA sequencing (MeRIP-seq). The streamlined protocol is easy to process and can produce results with high SN ratios。 产品特点: 1·Complete collection of MeRIP valiidated reagents to streamline the MeRIP method; 2·High signal to noise ratios using high affinity m6A monoclonal antibody and A/G magnetic beads ; 3.Stem cell validated; 4.The Magna MeRIP M6A Kit provides sufficient reagents for 10 MeRIP reactions using 5 μg of mRNA or 5 MeRIP reactions when 300 μg of total RNA is used; 5.Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals。 保存建议:在接收到艾德寄出的试剂盒后请按照说明书建议,使用不同的保存条件或温度来保存试剂盒内组分。 相关的资料,请下载参考附件。 |
» 本帖附件资源列表
-
欢迎监督和反馈:小木虫仅提供交流平台,不对该内容负责。
本内容由用户自主发布,如果其内容涉及到知识产权问题,其责任在于用户本人,如对版权有异议,请联系邮箱:xiaomuchong@tal.com - 附件 1 : A-17-10499-Magna_m6A_RNA甲基化免疫沉淀试剂盒-特定位点分析.pdf
- 附件 2 : A-P-9005-m6A_RNA甲基化定量检测试剂盒(比色法).pdf
- 附件 3 : SC-艾德科技-绝招在身!走遍天下!掌握表观遗传学前沿产品研究工具!.pdf
- 附件 4 : SC-艾德科技-萌货!奔跑吧!!RNA甲基化时代来了!!!.pdf
2017-02-09 09:17:27, 1.18 M
2017-02-09 09:18:02, 1.25 M
2017-02-09 09:18:51, 3.81 M
2017-02-09 09:18:59, 2.4 M
» 猜你喜欢
能源材料化学课题组招收硕士研究生8-10名
已经有11人回复
求材料调剂
已经有9人回复
材料专硕英一数二306
已经有5人回复
085600材料与化工调剂 324分
已经有9人回复
0703化学调剂
已经有12人回复
0703化学 305求调剂
已经有4人回复
0703化学调剂,求各位老师收留
已经有10人回复
271材料工程求调剂
已经有5人回复
281求调剂(0805)
已经有16人回复
304求调剂
已经有6人回复
» 抢金币啦!回帖就可以得到:
物理学 调剂
+1/89
济南大学林秀娟教授招收材料类博士生
+1/87
物理学 调剂
+1/85
物理学 调剂
+1/84
温州大学吕晶晶课题组2026年招生
+1/80
愿遇见你,遇见不止擦肩而过的缘分
+1/75
华南师范大学(211)博士招生- 电子、自动化、机械、生物学、物理相关专业
+2/42
上海交通大学电催化方向博后招聘-有锂电、高分子、燃料电池背景者优先
+1/31
【深圳理工大学】院士工作站招聘博士后-电催化和有机电化学
+1/23
浙江中医药大学副校长团队招聘药学/生物信息学等方向高校教师7名,报名通道已开启
+1/21
海南师范大学孙元元老师招生博士,名额1~2个,2026年9月份入学(光电/光热催化方向)
+1/17
南京理工大学2026级硕士生招生-张光普博导 &硕导
+2/16
南京医科大学-膜蛋白结构与功能课题组-招收2026级博士研究生
+1/11
上海科技大学招收有机化学方向招收2026级工程博士
+1/6
211/双一流石河子大学化学化工学院--电催化,CO2转化
+1/6
武汉纺织大学杰青团队招研究生(材料,化学,高分子,化工)
+1/4
课题组招收环境及相关专业调剂硕士研究生(欢迎优秀学生加入)
+1/2
福建师范大学海峡柔性电子学院招收2026调剂硕士
+1/2
巴塞罗那自治大学(UAB)-巴塞罗那材料研究所(ICMAB)招收博士研究生
+1/2
339求调剂
+1/1
★
ADTechnology(金币+1): 谢谢参与
ADTechnology(金币+1): 谢谢参与
![]() |
56楼2017-02-09 13:35:47



针对特定位点的 m6A RNA甲基化,全球顶级检测方法。具体参考如下:
回复此楼