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2016年新著——DNA复制：新进展（英文第二版）
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"DNA Replication: Current Advances" ed. by Hervé Seligmann Second edition ITexLi | 2016 | ISBN: 9533075937 | 707 pages | PDF | 35 MB This book offers to readers current trends in the field of DNA replication. The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. Contents Part 1 DNA Structure 1 DNA Structure: Alphabet Soup for the Cellular Soul 2 Replication Demands an Amendment of the Double Helix 3 Phosphorothioation: An Unusual Post-Replicative Modification on the DNA Backbone 4 Mitosis and DNA Replication and Life Origination Hydrate Hypotheses: Common Physical and Chemical Grounds Part 2 Mutations 5 Strand-specific Composition Bias in Bacterial Genomes 6 Mutation Patterns Due to Converging Mitochondrial Replication and Transcription Increase Lifespan, and Cause Growth Rate-Longevity Tradeoffs 7 Mitochondrial DNA Replication in Health and Disease 8 Damage and Replication Stress Responses Part 3 Replication Origins, Forks, Chromatine Organization 9 Relationship between Fork Progression and Initiation of Chromosome Replication in E. coli 10 Replication Origin Selection and Pre-Replication Complex Assembly 11 The Coordination between DNA Replication Initiation and Other Cell Cycle Events 12 The Organisation of Replisomes 13 Eukaryotic Replication Barriers: How, Why and Where Forks Stall 14 Control ofTelomeric DNA Replication: Genetics, Molecular Biology, and Physiology 15 Telomere Maintenance in Organisms without Telomerase 16 Eukaryote DNA Replication and Recombination: an Intimate Association Part 4 The Cell Cycle and Replication 17 Cell Cycle Regulation of DNA Replication in S. cerevisiae 18 Free Histones and the Cell Cycle 19 Involvement of Linker Histones in the Regulation of Replication Timing 20 Replication Timing: Evolution. Nuclear Organization and Relevance for Human Disease 21 The Silencing Face of DNA Replication: Gene Repression Mediated by DNA Replication Factors Part 5 Proteins in Replication 22 Faithful DNA Replication Requires Regulation of CDK Activity by Checkpoint Kinases 23 Regulation of the G1/S Transition in Adult Liver: Expression and Activation of the Cyclin Dependent Kinase Cdk1 in Differentiated Hepatocytes is Controlled by Extracellular Signals and is Crucial for Commitment to DNA Replication 24 Binding of Human MCM-BP with MCM2-7 Proteins 25 DNA Replication in Animal Systems Lacking Thioredoxin Reductase I Part 6 Replication and Diseases 26 Prevalence of Reactivation of Hepatitis В Virus DNA Replication in Rheumatoid Arthritis Patients 27 Oncogenic Aspects of HPV Infections of the Female Genital Tract 28 The Role of E2 Proteins in Papillomavirus DNA Replication 29 Topoisomerase I and II Expression in Recurrent Colorectal Cancer Cells: A Dubious Matter 30 Bacterial Genetics of Large Mammalian DNA Viruses: Bacterial Artificial Chromosomes as a Prerequisite for Efficiently Studying Viral DNA Replication and Functions  ITexLi | 2016 | ISBN: 9533075937 | 707 pages | PDF | 35 MB |
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