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Recent Trends in Antifungal Agents and Antifungal Therapy
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Recent Trends in Antifungal Agents and Antifungal Therapy Editors: Basak, Amit, Chakraborty, Ranadhir, Mandal, Santi M. (Eds.) Springer October 23, 2016 ISBN-10: 8132227808 Presents a top to bottom outline of natural and synthetic antifungal compounds Elaborates on the past and recent updates on antifungal peptides with their structure-function relationship Focuses on antifungal chemotherapy, structure-activity/function relationship and synthetic analogues which help in development of new compounds and drugs Fungal infections have taken a new spectrum due to the increased incidence of multi-drug resistant fungal pathogens. Freedom of choice for drugs to treat fungal infections is also narrow because of lesser probability of discovering drugs that would bypass affecting human cells and target fungal cells producing fewer side effects in patients. An approach has gained prominence in research is to look for bioactive antifungal compounds from natural to synthetic sources. It is necessary to discover new classes of antifungals to control the recent emergence of multi-drug resistant fungal infections. This book proposed a details top to bottom outline of antifungal compounds derived naturally or synthetically. The details of their modifications or synthetic analogues have been described, helpful to understand the structure-activity relationship which leads to new compound development in antifungal chemotherapy. Each chapter begins with a comprehensive, top-bottom in-depth discussion of antifungal agents with updated bibliographic references. This compendium will serve as a companion not only for Scientists, Researchers, and Professors, Medical Practitioners but also a valuable reference text for the university students. Contents 1 Fungi Fights Fungi: Tip-off in Antifungal Chemotherapy . . . 1 Santi M. Mandal, Anupam Roy, Debarati Paul, Suresh Korpole, Shanker Lal Shrivastava, Ranadhir Chakraborty, and Amit Basak 2 Essential Oil and Antifungal Therapy . . . . . . . . . . . . . . . . . . 29 Mohammad Moghaddam and Leila Mehdizadeh 3 Antifungal Peptides with Potential Against Pathogenic Fungi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 Camila G. Freitas and Octa??vio L. Franco 4 Lipopeptides: Status and Strategies to Control Fungal Infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97 Piyush Baindara and Suresh Korpole 5 Plant-Derived Antifungal Agents: Past and Recent Developments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 G.M. Vidyasagar 6 Recent Advancements in Combinational Antifungal Therapy and Immunotherapy . . . . . . . . . . . . . . . . . . . . . . . . 149 Sudarshan Singh Rathore, Jayapradha Ramakrishnan, and Thiagarajan Raman 7 Nanocarriers of Antifungal Agents . . . . . . . . . . . . . . . . . . . . 175 Sevgi G?ungo?? r and M. Sedef Erdal 8 Synthetic Compounds for Antifungal Chemotherapy . . . . . . 191 Rupa Pegu, Rohan Borah, and Sanjay Pratihar 9 Antifungal Therapy in Eye Infections: New Drugs, New Trends . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217 Joveeta Joseph and Savitri Sharma 10 Antifungal Susceptibility  |
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2016-09-25 09:10:38, 3.87 M
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