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[×ÊÔ´] Marine Pharmacognosy: Trends and Applications

Marine Pharmacognosy: Trends and Applications
By Se-Kwon Kim
2012
ISBN: 1439892296

Diverse and abundant, marine-derived bioactive compounds offer a plethora of pharmacologically active agents with the potential to produce valuable therapeutic entities. Marine-derived organisms, including some macroalgae, microalgae, blue-green algae, invertebrates, and vertebrates¨Dvalued in traditional Chinese medicine since ancient times¨Dare now recognized as rich sources of pharmaceutically active compounds. These factors, coupled with the growing need for novel bioactives for the treatment of severe human diseases such as cancer, diabetes, microbial infections, and inflammatory processes, has brought marine pharmaceuticals to the forefront of pharmacology. Marine Pharmacognosy: Trends and Applications provides a comprehensive account of marine-derived bioactive pharmaceuticals and their potential health benefits, including antioxidant, anticancer, antiviral, anticoagulant, antidiabetic, antiallergy, anti-inflammatory, antihypertensive, antibacterial, and radioprotective activities. Moreover, it discusses the sources, isolation and purification, chemistry, functionality interactions, applications, and industrial features of a variety of marine-derived pharmaceuticals. Marine pharmacognosy is a dynamic field that has been systematically investigated over the last 50 years, and the number of publications and patents are increasing every year. Bringing together a global team of experts, Marine Pharmacognosy: Trends and Applications reviews current research on marine-derived bioactive compounds and provides insight into future research on their potential as pharmacologically active agents.

Contents
Preface..............................................................................................................................................ix
Editor................................................................................................................................................xi
Contributors................................................................................................................................... xiii
Chapter 1 Past, Present, and Future of Marine Pharmacognosy...................................................1
Se-Kwon Kim
Chapter 2 Antidiabetic Compounds from Marine Organisms and Their Properties....................7
Miyuki Shirosaki and Tomoyuki Koyama
Chapter 3 Bioactive Compounds from Okinawan Marine Cyanobacteria.................................. 21
Toshiaki Teruya, Osamu Ohno, and Kiyotake Suenaga
Chapter 4 Bioactive Secondary Metabolites from Marine-Derived Fungi..................................27
Sherif S. Ebada and Peter Proksch
Chapter 5 Cytotoxic Briarane-Type Diterpenoids....................................................................... 53
Yonghong Liu, Xiuping Lin, Bin Yang, Juan Liu, Xuefeng Zhou, and Yan Peng
Chapter 6 Pharmacoanalytical Procedures for Chondroitin Present in Raw Materials and Biological Fluids..................................................................................65
Bradley Wright and Brian Lockwood
Chapter 7 Marine Natural Products Targeting Nuclear Factor ¦ÊB..............................................85
U. Sebnem Harput
Chapter 8 The Immunomodulatory Effect of Marine Algae on Allergic Response................. 101
Se-Kwon Kim, Thanh-Sang Vo, and Dai-Hung Ngo
Chapter 9 Pharmacological Effects of Marine-Derived Bioactive Peptides.............................. 107
Se-Kwon Kim, Dai-Hung Ngo, Thanh-Sang Vo, and Dai-Nghiep Ngo
Chapter 10 Sea Cucumber Saponins: Realization of Their Anticancer Effects.......................... 119
Se-Kwon Kim, S. W. A. Himaya, and Kyong-Hwa Kang
Chapter 11 Phlorotannins as Potential Antibacterial Agents from Marine Brown Algae.......... 129
Sung-Hwan Eom and Se-Kwon Kim
Chapter 12 Bioactive Molecules from Symbiotic Marine Dinoflagellates.................................. 137
Masaki Kita, Toshiyasu Inuzuka, Norihito Maru, and Daisuke Uemura
Chapter 13 Pharmacological Potential of Phlorotannins from Marine Brown Algae................. 153
BoMi Ryu and Se-Kwon Kim
Chapter 14 Microalgae as Sources of Biomaterials and Pharmaceuticals.................................. 161
Kyong-Hwa Kang and Se-Kwon Kim
Chapter 15 Marine Ascidians: A Promising Resource for Bioactive Compounds...................... 173
H. Abdul Jaffar Ali and M. Tamilselvi
Chapter 16 Chitosan and Its Derivatives for Treatment of Diabetic Complications................... 191
Se-Kwon Kim and Fatih Karadeniz
Chapter 17 Alkaloids as Pharmaceutical Agents from Marine Fungi......................................... 201
Se-Kwon Kim and Yong-Xin Li
Chapter 18 Pharmacological Effects and Prospects of Marine Algae in Promoting
Women¡¯s Health and Longevity................................................................................209
Se-Kwon Kim, Ratih Pangestuti, and A. B. Susanto
Chapter 19 Marine Sponge-Associated Microbes: A Source of Biologically
Active Metabolites..................................................................................................... 219
Se-Kwon Kim, Pradeep Dewapriya, and Yong-Xin Li
Chapter 20 Marine Actinobacteria: A Potential Source of Antifungal Compounds................... 231
R. Vijayakumar, A. Panneerselvam, and N. Thajuddin
Chapter 21 Marine Drugs: Treatment for Osteoporosis and Related Bone Diseases.................. 253
Jayachandran Venkatesan and Se-Kwon Kim
Chapter 22 Bioactive Compounds from Marine Sources for Gastrointestinal
Cancer Treatment......................................................................................................265
Se-Kwon Kim and Mustafa Zafer Karagozlu
Chapter 23 Marine Algae: Pharmacological Values and Anti-Inflammatory Effects................. 273
Se-Kwon Kim, Thanh-Sang Vo, and Dai-Hung Ngo
Contents vii
Chapter 24 Marine Microbial Pharmacognosy: Aspects and Prospects..................................... 281
Se-Kwon Kim and Ira Bhatnagar
Chapter 25 Pharmacognosy Prospects of Marine Algal Derivatives in the
Management of Skin Inflammation..........................................................................303
Se-Kwon Kim and Noel Vinay Thomas
Chapter 26 Antidiabetic Effect of Dieckol, a Marine Polyphenol, and Its
Mechanisms of Blood Glucose Regulation............................................................... 313
Seung-Hong Lee and You-Jin Jeon
Chapter 27 Allergy and Its Remedies from Marine Sources....................................................... 325
Ramjee Pallela, Ira Bhatnagar, Pranjal Chandra, and Se-Kwon Kim
Chapter 28 Anticancer Mechanisms of Actin Depolymerization Agent Pectenotoxin-2............ 335
Gi-Young Kim and Yung Hyun Choi
Chapter 29 Marine Mucin: A Prospective Cosmetic and Pharmaceutical.................................. 347
Se-Kwon Kim, Fatih Karadeniz, and Mustafa Zafer Karagozlu
Chapter 30 Neuropharmacological Properties of Marine Plants................................................. 355
Suengmok Cho and Se-Kwon Kim
Chapter 31 Antiparasitic Secondary Metabolites from Marine Actinobacteria.......................... 373
D. Dhanasekaran, N. Thajuddin, and A. Panneerselvam
Chapter 32 Pharmaceutical Aspect of Metabolites from Marine Algae on Skin Health............ 385
Jung-Ae Kim and Se-Kwon Kim
Chapter 33 Clues for Cancer from Ocean-Derived Molecules and Role of In Silico
Techniques in Anticancer Drug Discovery............................................................... 393
G. Dicky John Davis, Veeresh Kumar Sali, and Hannah R. Vasanthi
Chapter 34 Anticancer Compounds from Marine Microorganisms............................................409
Hee Jae Shin
Index..............................................................................................................................................425

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