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等温微量热法对固态药物的表征 已有1人参与
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| Drug product development and manufacture requires numerous studies to ensure that the purity, quality, stability and safety of the product are characterized and well understood. A large percentage of drugs are formulated as solids. Since a given pharmaceutical chemical entity can often exist in more than one thermodynamically or kinetically stable crystal form, and often can also exist as a glass (amorphous state), it is important to characterize the properties of the crystalline and amorphous states and the factors affecting their interconversion. The ability of a compound to exist in these different solid state forms is known as polymorphism. |
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2楼2016-06-25 09:32:08