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WOS:000358617800109
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ooq007(liouzhan654´ú·¢): ½ð±Ò+5, ¸Ðл½»Á÷ 2016-06-20 10:28:31
Study on Histocompatibility and Biodegradability of Polylactic Acid Gel in Rats
×÷Õß:Wang, T (Wang, Ting)[ 1 ] ; Cai, PL (Cai, Pei-Ling)[ 1 ] ; Heng, X (Heng, Xin)[ 1 ] ; Cheng, LJ (Cheng, Li-Jia)[ 1 ]
±àÕß:Zhang, Z
PROCEEDINGS OF THE 2015 INTERNATIONAL CONFERENCE ON MATERIAL SCIENCE AND APPLICATIONS (ICMSA 2015)
´ÔÊé: APR
¾í: 3  Ò³: 597-600
³ö°æÄê: 2015
»áÒéÃû³Æ
»áÒé: International Conference on Material Science and Application (ICMSA)
»áÒ鵨µã: Suzhou, PEOPLES R CHINA
»áÒéÈÕÆÚ: JUN 13-14, 2015
ÕªÒª
Objective: To investigatethe effects on histocompatibility and biodegradability of bioabsorbablepolylacticacid (PLA) gelin rats. Methods: Longitudinal incision of 30 mm was made along the spine, and subcutaneous tissues were separated bluntly to make four subcutaneous pouches, and PLA gel of different molecular weight (5, 10 and 20 kD) was implanted into the pouches. 4, 7, 11 and 14 weeks after implantation, the samples and surrounding tissues were collected to perform HE staining; meanwhile, the samples were weighted and compared after drying. Results: There were few inflammatory cells accumulations in tissues treated with different molecular weight PLA gel. The degradation rate of 5 kD-PLA gel was faster than other groups. With increase of the molecular weight of PLA gel, the degradation rate was gradually decreased. Conclusion: Our findings indicated that PLA gel had good biocompatibility and a definite degrading effect, which could be further used in surgery.
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×÷Õ߹ؼü´Êolylactic Acid Gel; histocompatibility; Biodegradability; Postoperative Adhesions
KeyWords Plus:IN-VIVO
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ͨѶ×÷ÕßµØÖ·: Cheng, LJ (ͨѶ×÷Õß)
              Chengdu Univ, Sch Med & Nursing, 1 Shi Ling St,Cheng Luo Ave, Chengdu 610106, Sichuan, Peoples R China.
µØÖ·:
              [ 1 ] Chengdu Univ, Sch Med & Nursing, Chengdu 610106, Sichuan, Peoples R China
µç×ÓÓʼþµØÖ·:violetwt@qq.com; caipeiling@cdu.edu.cn; chenglijia@cdu.edu.cn
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ATLANTIS PRESS, 29 AVENUE LAVMIERE, PARIS, 75019, FRANCE
Àà±ð / ·ÖÀà
Ñо¿·½Ïò:Materials Science
Web of Science Àà±ð:Materials Science, Multidisciplinary
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ÎÄÏ×ÀàÐÍroceedings Paper
ÓïÖÖ:English
Èë²ØºÅ: WOS:000358617800109
ISBN:978-94-62520-75-2
ISSN: 2352-541X
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Web of Science ºËÐĺϼ¯ÖÐµÄ "ÒýÓõIJο¼ÎÄÏ×": 12
Web of Science ºËÐĺϼ¯ÖÐµÄ "±»ÒýƵ´Î": 0
3Â¥2016-06-20 10:23:18
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