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ß²Üó¤´Ý”(fjtony163´ú·¢): ½ð±Ò+50, ´ú·¢ 2016-06-26 04:49:38
fjtony163: ·­ÒëEPI+1, ´ú·¢ 2016-06-26 04:49:44
The measurement for complexation stability constants of Baicalin and metal ion
Abstract: Baicalin possess extensive pharmacological activities such as antisepsis and anti-inflammation, drop of blood pressure, diuresis, liver protection and free radicals scavenging, etc.. It is one of main effective components in Scutellaria Baicalensis of traditional Chinese medicine. Baicalin and some trace metal ions can generate complex, which improves biological activity and reduces the toxicity of metals. In this experiment, potassium hydroxide solution is used to titrate the solution of baicalin including copper ion, cobalt ion, aluminium ion and chromium ion. Leici automatic potentiometric titrator is adopted to record its reaction process. The stability constants of baicalin and metal complex ion are calculated by generating four methods, namely, function intercept method, half-integer method, segmental fitting method and direct computing method.
Keywords: Baicalin, metal ion, intercept method, half-integer method, segmental fitting method,direct computing method.

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