| 查看: 817 | 回复: 12 | |||
| 【奖励】 本帖被评价10次，作者york6999增加金币 8 个 | |||
[资源]
Pharmacological Mechanisms in Alzheimer's Therapeutics
|
|||
|
Pharmacological Mechanisms in Alzheimer's Therapeutics by Claudio Cuello Springer Oct. 31, 2007 ISBN: 0387978798 Contents xi FOREWORDS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v William H. Thies Theodore L. Sourkes PREFACE FROM THE EDITOR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix A. Claudio Cuello LIST OF CONTRIBUTORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv 1. OVERVIEW OF THE ALZHEIMER’S DISEASE PATHOLOGY AND POTENTIAL THERAPEUTIC TARGETS . . . . . . . . . . . . . 1 A. Claudio Cuello 2. TRIAL DESIGNS AND OUTCOMES TO MONITOR NOVEL THERAPEUTICS IN ALZHEIMER’S DISEASE . . . . . . . . . . . . 28 Serge Gauthier 3. THE PHARMACOLOGICAL TREATMENT OF ALZHEIMER’S DISEASE WITH CHOLINESTERASE INHIBITORS AND MEMANTINE . . . . . . . . . . . . . . . . . . 36 Gordon Keith Wilcock 4. M1 MUSCARINIC AGONISTS: A COMPREHENSIVE THERAPY AGAINST MAJOR HALLMARKS OF ALZHEIMER’S DISEASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Abraham Fisher 5. CHOLINERGIC NEURODEGENERATION IN ALZHEIMER’S DISEASE: BASIS FOR NERVE GROWTH FACTOR THERAPY. . . . . Ahmad Salehi, Alexander Kleshevnikov, and William C. Mobley 6. THE RATIONALE FOR GLUTAMATERGIC THERAPY IN ALZHEIMER’S DISEASE. . . . . . . . . . . . . . . . . . . . . . . . . . . 105 Paul T. Francis 7. SECRETASES AS PHARMACOLOGICAL TARGETS IN ALZHEIMER’S DISEASE. . . . . . . . . . . . . . . . . . . . . . . . . . . 113 Nigel M. Hooper and Emma R. L. C. Vardy 8. g-SECRETASE AS A TARGET FOR ALZHEIMER’S DISEASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 Michael S. Wolfe 9. THE RATIONALE FOR AN IMMUNOLOGICAL APPROACH TO ALZHEIMER’S THERAPEUTICS . . . . . . . . 141 Dave Morgan 10. NEUROINFLAMMATION, ALZHEIMER DISEASE, AND OTHER AGING DISORDERS . . . . . . . . . . . . . . . . . . . . . 149 Edith G. McGeer and Patrick L. McGeer 11. NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) AND DERIVED Ab42-LOWERING MOLECULES FOR TREATMENT AND PREVENTION OF ALZHEIMER’S DISEASE (AD) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 Sascha Weggen, Eva Czirr, Stefanie Leuchtenberger, and Jason Eriksen 12. THE POTENTIAL APPLICATION OF ANTIOXIDANT AGENTS IN ALZHEIMER DISEASE THERAPEUTICS. . . . . 194 Paula I. Moreira, Mark A. Smith, Xiongwei Zhu, Akihiko Nunomura, and George Perry 13. APOLIPOPROTEIN E: A POTENT GENE-BASED THERAPEUTIC TARGET FOR THE TREATMENT OF SPORADIC ALZHEIMER’S DISEASE. . . . . . . . . . . . . . . . 212 Judes Poirier 14. TAU PATHOLOGY AS A TARGET IN ALZHEIMER’S THERAPEUTICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223 Khalid Iqbal and Inge Grundke-Iqbal 15. DESIGN OF INHIBITORS OF AMYLOID-b MISFOLDING AND AGGREGATION FOR ALZHEIMER’S THERAPY . . . . 238 Lisbell D. Estrada, Cristian Lasagna, and Claudio Soto 16. POTENTIAL APPLICATIONS OF GLYCOSAMINOGLYCANRELATED COMPOUNDS IN ALZHEIMER’S DISEASE . . . . 255 Céline Morissette, Diane Lacombe, Xianqi Kong, Ahmed Aman, Pascale Krzywkowski, Lioudmila Rodionova, Mounia Azzi, Daniel Delorme, and Barry D. Greenberg 17. MULTIFUNCTIONAL NEUROPROTECTIVE DRUGS FOR THE TREATMENT OF ALZHEIMER’S DISEASE. . . . . 274 Cornelis J. Van der Schyf, Werner J. Geldenhuys, and Moussa B. H. Youdim 18. INTERPRETING CLINICAL STUDIES OF PUTATIVE THERAPEUTICS FOR ALZHEIMER’S DISEASE: THE CASE OF STATINS AND NSAIDs . . . . . . . . . . . . . . . . . . 296 Benjamin Wolozin INDEX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309 |
回复此楼» 本帖附件资源列表
-
欢迎监督和反馈：小木虫仅提供交流平台，不对该内容负责。
本内容由用户自主发布，如果其内容涉及到知识产权问题，其责任在于用户本人，如对版权有异议，请联系邮箱：xiaomuchong@tal.com - 附件 1 : Pharmacological_Mechanisms_in_Alzheimers_Therapeutics.pdf
2016-05-08 14:17:39, 3.05 M
» 收录本帖的淘帖专辑推荐
 药学专业课8475 |
» 猜你喜欢
268求调剂
已经有8人回复
-
26申博
已经有4人回复
-
211本，11408一志愿中科院277分，曾在中科院自动化所实习
已经有7人回复
-
求调剂，总分315，考的生物医药，一志愿湖南师范大学。调剂到任何专业都可以
已经有3人回复
-
材料专硕306英一数二
已经有7人回复
-
材料工程专硕274一志愿211求调剂
已经有6人回复
-
一志愿南京大学，080500材料科学与工程，调剂
已经有4人回复
-
332求调剂
已经有5人回复
-
271求调剂
已经有14人回复
-
275求调剂
已经有4人回复
» 本主题相关价值贴推荐，对您同样有帮助:
7楼2016-05-11 09:26:11
12楼2016-10-23 18:32:21
简单回复
2016-05-08 18:57
回复
五星好评 顶一下，感谢分享！
kinggbp3楼
2016-05-09 06:13
回复
顶一下，谢谢分享 发自小木虫Android客户端
2016-05-09 09:51
回复
五星好评 顶一下，感谢分享！
2016-05-09 22:14
回复
五星好评 顶一下，感谢分享！
work0376楼
2016-05-10 09:59
回复
五星好评 顶一下，感谢分享！
chemosky8楼
2016-05-11 15:00
回复
五星好评 顶一下，感谢分享！
2016-05-11 15:03
回复
五星好评 顶一下，感谢分享！
dahuamao2910楼
2016-05-22 17:49
回复
五星好评 顶一下，感谢分享！
yaoxuexuezi11楼
2016-10-20 22:58
回复
五星好评 顶一下，感谢分享！
wslld13楼
2017-03-16 22:21
回复
五星好评 顶一下，感谢分享！
5