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760305201zdy银虫 (小有名气)
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45.大神们帮忙翻译一篇文献，急急急
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就是这篇文献。下面有文献原文，谢谢大神们！！ StreptomeDB: a resource for natural compounds isolated from Streptomyces species By Lucas, Xavier; Senger, Christian; Erxleben, Anika; Gruening, Bjoern A.; Doering, Kersten; Mosch, Johannes; Flemming, Stephan; Guenther, Stefan From Nucleic Acids Research (2013), 41(D1), D1130-D1136. Language: English, Database: CAPLUS, DOI:10.1093/nar/gks1253 Bacteria from the genus Streptomyces are very important for the prodn. of natural bioactive compds. such as antibiotic, antitumor or immunosuppressant drugs. Around two-thirds of all known natural antibiotics are produced by these bacteria. An enormous quantity of crucial data related to this genus has been generated and published, but so far no freely available and comprehensive database exists. Here, we present StreptomeDB (https://www.pharmaceuticalbioinformatics. de/streptomedb/). To the best of our knowledge, this is the largest database of natural products isolated from Streptomyces. It contains >2400 unique and diverse compds. from >1900 different Streptomyces strains and substrains. In addn. to names and mol. structures of the compds., information about source organisms, refs., biol. role, activities and synthesis routes (e.g. polyketide synthase derived and non-ribosomal peptides derived) is included. Data can be accessed through queries on compd. names, chem. structures or organisms. Extn. from the literature was performed through automatic text mining of thousands of articles from PubMed, followed by manual curation. All annotated compd. structures can be downloaded from the website and applied for in silico screenings for identifying new active mols. with undiscovered properties. |
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2016-04-18 21:34:25, 3.43 M
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