24小时热门版块排行榜    

查看: 369  |  回复: 0

TAINST

铁虫 (正式写手)

[交流] DSC表征膜蛋白和配体的结合

Like ITC, DSC is a valuable approach for studying binding between a biological macromolecule and a ligand such as another biopolymer or a drug. Unlike ITC, DSC allows the thermodynamics that drive binding to be correlated, at least to a degree, with conformational changes in the macromolecule caused by the binding reaction. DSC is particularly useful for characterizing very tight or slow binding interactions. DSC also allows characterization of binding reactions that are incompatible with the organic solvent requirements of some ITC experiments (i.e., where ligand solubility for an ITC experiment requires concentrations of organic solvent not tolerated by the protein).
回复此楼

» 本帖附件资源列表

  • 欢迎监督和反馈:小木虫仅提供交流平台,不对该内容负责。
    本内容由用户自主发布,如果其内容涉及到知识产权问题,其责任在于用户本人,如对版权有异议,请联系邮箱:xiaomuchong@tal.com
  • 附件 1 : DSC表征膜蛋白和配体的结合.pdf
  • 2016-03-31 16:49:06, 1.74 M

» 猜你喜欢

已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 TAINST 的主题更新
普通表情 高级回复 (可上传附件)
信息提示
请填处理意见