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Selective recent publications (* corresponding or co-corresponding author):
1.He, T., S. Liu, S. Chen, J. Ye, X. Wu, Z. Bian and X. Chen (2018). "The p38 MAPK Inhibitor SB203580 Abrogates Tumor Necrosis Factor-Induced Proliferative Expansion of Mouse CD4+Foxp3+ Regulatory T Cells." Frontiers in Immunology 9(1556).
2.Zou, H., R. Li, H. Hu, Y. Hu and X. Chen (2018). "Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents." Frontiers in Immunology 9(594).
3.Nie, Y., J. He, H. Shirota, A. L. Trivett, Yang, D. M. Klinman, J. J. Oppenheim and X. Chen (2018). "Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer." Sci Signal 11(511).
4.Liu, S. and X. Chen (2018). "Dietary therapy may be sufficient for type 1 diabetes treatment." Cell Mol Immunol 15(2): 85-87.
5.Li, P., Y. Zheng and X. Chen (2017). "Drugs for Autoimmune Inflammatory Diseases: From Small Molecule Compounds to Anti-TNF Biologics." Front Pharmacol 8: 460.
6.Chen, X. and J. J. Oppenheim (2017). "Targeting TNFR2, an immune checkpoint stimulator and oncoprotein, is a promising treatment for cancer." Sci Signal 10(462).
7.Nie, Y., Yang, A. Trivett, Z. Han, H. Xin, X. Chen and J. J. Oppenheim (2017). "Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors." Sci Rep 7(1): 14186.
8.Chen, X. and J. J. Oppenheim (2016). "Therapy: Paradoxical effects of targeting TNF signalling in the treatment of autoimmunity." Nat Rev Rheumatol 12(11): 625-626.
9.Zaragoza, B., X. Chen, J. J. Oppenheim, A. Baeyens, S. Gregoire, D. Chader, G. Gorochov, M. Miyara and B. L. Salomon (2016). "Suppressive activity of human regulatory T cells is maintained in the presence of TNF." Nat Med 22(1): 16-17.
10.Yan, F., R. Du, F. Wei, H. Zhao, J. Yu, C. Wang, Z. Zhan, T. Ding, X. Ren, X. Chen and H. Li (2015). "Expression of TNFR2 by regulatory T cells in peripheral blood is correlated with clinical pathology of lung cancer patients." Cancer Immunol Immunother 64(11): 1475-1485.
11.Hamano, R., X. Wu, Y. Wang, J. J. Oppenheim and X. Chen (2015). "Characterization of MT-2 cells as a human regulatory T cell-like cell line." Cell Mol Immunol 12(6): 780-782.
12.Chen, X., J. Willette-Brown, X. Wu, Y. Hu, O. M. Howard, Y. Hu and J. J. Oppenheim (2015). "IKKalpha is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells." FASEB J 29(2): 443-454.
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