澳门大学陈新教授 (Professor Xin CHEN) 课题组2018年招收研究助理
要求: 具有生物、医药相关学科学位,熟悉动物实验及细胞操作技术,具有免疫学背景优先。对科学研究有强烈兴趣,为人诚信,工作勤奋,善于沟通,有独立思考及工作能力,博士后及博士生申请者需有发表SCI文章经验,英文水平需要符合澳门大学要求。
研究方向: 免疫调节机制及免疫药理
薪酬:遵循澳门政府及澳门大学的有关规定。
联系方式: 欢迎直接联系陈新教授(Professor Xin CHEN)(xchen@umac.mo)。
申请方式: 网上报名,具体报名及招生要求请参阅澳门大学研究生院网页(http://www.umac.mo/grs/cn/admissions.php)
Selective recent publications (* corresponding or co-corresponding author):
1. Yingjie Nie, Jiang He, Hidekazu Shirota, Anna L. Trivett, De Yang, Dennis M. Klinman, Joost J. Oppenheim, Xin Chen*. Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer. Science Signaling 2018. Jan 2. 11(511): pii: eaan0790. pii: eaan0790. doi: 10.1126/scisignal.aan0790
2. Shuoyang Liu and Xin Chen*. Dietary Therapy May Be Sufficient for Type 1 Diabetes Treatment. Cellular and Molecular Immunology. 2018 Feb;15(2):85-87. doi: 10.1038/cmi.2017.56.
3. Ping Li, Ying Zheng and Xin Chen*. Drugs for Autoimmune Inflammatory Diseases: from Small Molecule Compounds to anti-TNF Biologics. Frontiers in Pharmacology. 2017 Jul 12;8:460. doi: 10.3389/fphar.2017.00460.
4. Xin Chen* and J.J. Oppenheim, Targeting TNFR2, an immune checkpoint stimulator and oncoprotein, is a promising treatment for cancer. Science Signaling 2017. 10(462). pii: eaal2328. doi: 10.1126/scisignal.aal2328
5. Yingjie Nie, De Yang, Anna Trivett, Haiyun Xin, Zhen Han, Xin Chen, Joost J. Oppenheim. Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Big Solid Tumors. Scientific Reports 2017 Oct 27;7(1):14186. doi: 10.1038/s41598-017-14655-8.
6. Xin Chen*, and Joost J Oppenheim. Paradoxical effects of anti-TNF treatment of autoimmunity. Nature Reviews Rheumatology. 2016. 2016 Nov;12(11):625-626. doi: 10.1038/nrrheum.2016.145.
7. B Zaragoza, Xin Chen, JJ Oppenheim, D Chader, M Miyara and BL Salomon. Suppressive activity of human Treg cells is maintained in the presence of TNF. Nature Medicine. 2016 Jan 22:16-17. doi: 10.1038/nm.4019.
8. Fan Yan, Ruijuan Du, Feng Wei, Hua Zhao, Jingpu Yu, Changli Wang, Zhongli Zhan, TingTing Ding, Xiubao Ren, Xin Chen*, Hui Li. Expression of TNFR2 by regulatory T cells in the peripheral blood is correlated to the clinicopathology of lung cancer patients. Cancer Immunology, Immunotherapy. 2015 Nov;64(11):1475-85.
9. Ryoko Hamano, Xueqiang Wu, Yitao Wang, Joost J Oppenheim and Xin Chen*. Characterization of MT-2 cells as a human regulatory T cell-like cell line. Cellular & Molecular Immunology. 2015 Nov;12(6):780-2.
10. Xin Chen*, Jami Willette-Brown, Xueqiang Wu, Ya Hu, O.M. Zack Howard, Yinling Hu and Joost J Oppenheim. IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells. FASEB J. 2015, Feb;29(2):443-54.
PI学术背景,请参见: http://www.umac.mo/sklqrcm/academic_staff/xchen_ch.html
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